Background Catheter-based pulmonary vein isolation is an effective treatment for
paroxysmal atrial fibrillation. Pulsed field ablation, which delivers microsecond high-voltage …

Pulsed field ablation (PFA) is an emerging technology for the treatment of atrial fibrillation
(AF), for which pre-clinical and early-stage clinical data are suggestive of some degree of …

Background: Pulsed field ablation is a novel nonthermal cardiac ablation modality using
ultra-rapid electrical pulses to cause cell death by a mechanism of irreversible …

Atrial fibrillation is the most common sustained cardiac arrhythmia and is associated with
considerable morbidity and mortality. Electrically isolating the pulmonary veins from the left …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and catheter
ablation, which can be used in symptomatic patients refractory to antiarrhythmic therapy …

Background: The inspIRE study (Study for Treatment of Paroxysmal Atrial Fibrillation [PAF]
by Pulsed Field Ablation [PFA] System With Irreversible Electroporation [IRE]) evaluated …

Background Because of its safety,“single-shot” pulsed field ablation (PFA) catheters have
been developed for pulmonary vein isolation (PVI). However, most atrial fibrillation (AF) …

Background: Phrenic nerve palsy is a well-known complication of cardiac ablation, resulting
from the application of direct thermal energy. Emerging pulsed field ablation (PFA) may …

Background: Pulsed field ablation (PFA) is a nonthermal energy with potential safety
advantages over radiofrequency ablation. This study investigated a novel PFA system—a …

Background The ADVENT randomized trial revealed no significant difference in 1-year
freedom from atrial arrhythmias (AA) between thermal (radiofrequency/cryoballoon) and …