The role of α7-nAChR-mediated PI3K/AKT pathway in lung cancer induced by nicotine

Z He, Y Xu, Z Rao, Z Zhang, J Zhou, T Zhou… - Science of the Total …, 2024 - Elsevier
Nicotine enters the environment mainly through human activity, as well as natural sources.
This review article examines the increasing evidence implicating nicotine in the initiation …

Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: understandings from pharmacological point of view

F Mokhfi, M Al Amin, M Zehravi, SH Sweilam… - Chemico-Biological …, 2024 - Elsevier
This review aims to summarize the role of alkaloids as potential modulators of the
PI3K/Akt/mTOR (PAMT) pathway in cancer therapy. The PAMT pathway plays a critical role …

miRNA-Seq tissue diagnostic signature: a novel model for NSCLC subtyping

R Charkiewicz, A Sulewska, A Charkiewicz… - International Journal of …, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) encompasses distinct histopathological subtypes,
namely adenocarcinoma (AC) and squamous cell lung carcinoma (SCC), which require …

[HTML][HTML] Personalizing Therapy Outcomes through Mitogen-Activated Protein Kinase Pathway Inhibition in Non-Small Cell Lung Cancer

H Alsharoh, P Chiroi, E Isachesku, RA Tanasa, OL Pop… - Biomedicines, 2024 - mdpi.com
Lung cancer (LC) is a highly invasive malignancy and the leading cause of cancer-related
deaths, with non-small cell lung cancer (NSCLC) as its most prevalent histological subtype …

[HTML][HTML] Impact of Nordihydroguaiaretic Acid on Proliferation, Energy Metabolism, and Chemosensitization in Non-Small-Cell Lung Cancer (NSCLC) Cell Lines

C Chipón, P Riffo, L Ojeda, M Salas, RA Burgos… - International Journal of …, 2024 - mdpi.com
Lung cancer (LC) is the leading cause of cancer death worldwide. LC can be classified into
small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC), with the last …

[HTML][HTML] Detection of High-Risk Human Papillomavirus (HPV), p16 and EGFR in Lung Cancer: Insights from the Mediterranean Region of Turkey

AS Alikanoğlu, İA Karaçay - Viruses, 2024 - mdpi.com
Human papillomavirus (HPV) is an oncogenic DNA virus that plays a role in different cancer
types. The aim of this study was to detect the prevalence and types of HPV and its relation …

A Paradigm Shift in Non-Small-Cell Lung Cancer (NSCLC) Diagnostics: From Single Gene Tests to Comprehensive Genomic Profiling

U Zameer, W Shaikh, AM Khan - Cancer Informatics, 2024 - journals.sagepub.com
Lung cancer imposes a burden on the health care system worldwide affecting 2 million
people and causing 1.8 million deaths in 2021. More than 85% of all lung cancer cases are …

Detection of High-Risk Human Papillomavirus (HPV) and Their Genotypes in Lung Cancer: Insights from the Mediterranean Region of Turkey

AS Alikanoğlu, İA Karaçay - 2024 - preprints.org
Lung cancer is the leading cause of cancer death worldwide therefore studies about the
etiological factors and carcinogenesis are important. The aim of the study is to detect the …

[PDF][PDF] BIOMEDICAL SCIENCES

MS AKILANDESWARI - 2023 - ssr.alagappauniversity.ac.in
Cancer is a global issue that represents a pathological manifestation of uncontrolled cell
division. Normal cells subject to common oncogenic stimuli ultimately transform and become …

Biomarker Profiles And Treatment Patterns In Patients With Advanced Non-Small Cell Lung Cancer: A Real-World Database Analysis

Z Niu - 2024 - elischolar.library.yale.edu
Background: With the rapidly evolving treatment options for patients with advance-staged
Non-Small Cell Lung Cancer (NSCLC), the National Comprehensive Cancer Network …