Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

An overview of microneedle applications, materials, and fabrication methods

ZF Rad, PD Prewett, GJ Davies - Beilstein journal of …, 2021 - beilstein-journals.org
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and
therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics …

Photo-inspired antibacterial activity and wound healing acceleration by hydrogel embedded with Ag/Ag@ AgCl/ZnO nanostructures

C Mao, Y Xiang, X Liu, Z Cui, X Yang, KWK Yeung… - ACS …, 2017 - ACS Publications
Ag/Ag@ AgCl/ZnO hybrid nanostructures are embedded in a hydrogel by a simple two-step
technique. The Ag/Ag@ AgCl nanostructures are assembled in the hydrogel via ultraviolet …

Glial responses to implanted electrodes in the brain

JW Salatino, KA Ludwig, TDY Kozai… - Nature biomedical …, 2017 - nature.com
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …

Ultraflexible nanoelectronic probes form reliable, glial scar–free neural integration

L Luan, X Wei, Z Zhao, JJ Siegel, O Potnis… - Science …, 2017 - science.org
Implanted brain electrodes construct the only means to electrically interface with individual
neurons in vivo, but their recording efficacy and biocompatibility pose limitations on scientific …

Brain tissue responses to neural implants impact signal sensitivity and intervention strategies

TDY Kozai, AS Jaquins-Gerstl… - ACS chemical …, 2015 - ACS Publications
Implantable biosensors are valuable scientific tools for basic neuroscience research and
clinical applications. Neurotechnologies provide direct readouts of neurological signal and …

A materials roadmap to functional neural interface design

SM Wellman, JR Eles, KA Ludwig… - Advanced functional …, 2018 - Wiley Online Library
Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

Biointegrated and wirelessly powered implantable brain devices: A review

R Das, F Moradi, H Heidari - IEEE transactions on biomedical …, 2020 - ieeexplore.ieee.org
Implantable neural interfacing devices have added significantly to neural engineering by
introducing the low-frequency oscillations of small populations of neurons known as local …

Flexible electrodes for in vivo and in vitro electrophysiological signal recording

M Zhu, H Wang, S Li, X Liang, M Zhang… - Advanced …, 2021 - Wiley Online Library
A variety of electrophysiological signals (electrocardiography, electromyography,
electroencephalography, etc.) are generated during the physiological activities of human …

Neural stimulation and recording with bidirectional, soft carbon nanotube fiber microelectrodes

F Vitale, SR Summerson, B Aazhang, C Kemere… - ACS …, 2015 - ACS Publications
The development of microelectrodes capable of safely stimulating and recording neural
activity is a critical step in the design of many prosthetic devices, brain–machine interfaces …