Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

MA La Merrill, LN Vandenberg, MT Smith… - Nature Reviews …, 2020 - nature.com
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with
hormone action, thereby increasing the risk of adverse health outcomes, including cancer …

[HTML][HTML] Impacts of endocrine disrupting chemicals on reproduction in wildlife and humans

VL Marlatt, S Bayen, D Castaneda-Cortès… - Environmental …, 2022 - Elsevier
Endocrine disrupting chemicals (EDCs) are ubiquitous in aquatic and terrestrial
environments. The main objective of this review was to summarize the current knowledge of …

[HTML][HTML] Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals

G Delbes, M Blázquez, JI Fernandino, P Grigorova… - Environmental …, 2022 - Elsevier
Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders

CL Schwartz, S Christiansen, AM Vinggaard… - Archives of …, 2019 - Springer
Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Diet as a source of exposure to environmental contaminants for pregnant women and children from six European countries

E Papadopoulou, LS Haug, AK Sakhi… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Pregnant women and children are especially vulnerable to exposures to food
contaminants, and a balanced diet during these periods is critical for optimal nutritional …

Endocrine disrupting chemicals impact on ovarian aging: Evidence from epidemiological and experimental evidence

T Ding, W Yan, T Zhou, W Shen, T Wang, M Li… - Environmental …, 2022 - Elsevier
Endocrine-disrupting chemicals (EDCs) are ubiquitous in daily life, but their harmful effects
on the human body have not been fully explored. Recent studies have shown that EDCs …

Cellular and molecular features of EDC exposure: consequences for the GnRH network

D Lopez-Rodriguez, D Franssen, J Bakker… - Nature Reviews …, 2021 - nature.com
The onset of puberty and the female ovulatory cycle are important developmental milestones
of the reproductive system. These processes are controlled by a tightly organized network of …

Endocrine-disrupting chemicals and their effects on puberty

D Lopez-Rodriguez, D Franssen, S Heger… - Best practice & research …, 2021 - Elsevier
Sexual maturation in humans is characterized by a unique individual variability. Pubertal
onset is a highly heritable polygenic trait but it is also affected by environmental factors such …

Cumulative exposure to phthalates and their alternatives and associated female reproductive health: body burdens, adverse outcomes, and underlying mechanisms

X Weng, Q Zhu, C Liao, G Jiang - Environmental Science & …, 2023 - ACS Publications
The global birth rate has recently shown a decreasing trend, and exposure to environmental
pollutants has been identified as a potential factor affecting female reproductive health …

Prenatal exposure to di (2-ethylhexyl) phthalate causes long-term transgenerational effects on female reproduction in mice

E Brehm, S Rattan, L Gao, JA Flaws - Endocrinology, 2018 - academic.oup.com
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer in many consumer products.
Although DEHP is a known endocrine disruptor, little is known about the effects of DEHP …