[HTML][HTML] Diabetes mellitus—Progress and opportunities in the evolving epidemic

ED Abel, AL Gloyn, C Evans-Molina, JJ Joseph… - Cell, 2024 - cell.com
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …

The insulin resistant brain: impact on whole-body metabolism and body fat distribution

M Heni - Diabetologia, 2024 - Springer
Insulin exerts its actions not only on peripheral organs but is also transported into the brain
where it performs distinct functions in various brain regions. This review highlights recent …

The Influence of Menstrual Cycle Phases on Maximal Strength Performance in Healthy Female Adults: A Systematic Review with Meta-Analysis

M Niering, N Wolf-Belala, J Seifert, O Tovar… - Sports, 2024 - mdpi.com
Maximal strength is a significant factor in achieving peak performance and injury prevention
in athletes. In individualization strategies for the efficient development of athletes, it is …

Glycaemic fluctuations across the menstrual cycle: possible effect of the brain

J Hummel, S Kullmann, R Wagner… - The Lancet Diabetes & …, 2023 - thelancet.com
Epidemiological research has identified a lower risk for type 2 diabetes and cardiovascular
disease in women who are premenopausal than in men. 1, 2 However, after menopause …

Liver-specific actions of GH and IGF1 that protect against MASLD

RD Kineman, M del Rio-Moreno… - Nature Reviews …, 2024 - nature.com
Metabolic dysfunction-associated steatotic liver disease (MASLD; also known as
nonalcoholic fatty liver disease) is a chronic condition associated with metabolic syndrome …

Sex differences in insulin induced hippocampus functional connectivity during visual food cue presentation

S Zhao, R Veit, L Semeia, J Hummel… - The Journal of …, 2024 - academic.oup.com
Aims Central insulin has been shown to regulate eating behavior and cognitive processes in
a sex-specific manner. Besides memory, the hippocampus is pivotal in the control of …

[HTML][HTML] Impact of physiological fluctuations of sex hormones during the menstrual cycle on glucose metabolism and the gut microbiota

A Schieren, S Koch, T Pecht… - Experimental and clinical …, 2024 - thieme-connect.com
Diabetes mellitus is one of the most prevalent chronic diseases. Previous studies have
shown differences in glucose metabolism between males and females. Moreover, difficulties …

Brain insulin action in women

S Starling - Nature Reviews Endocrinology, 2023 - nature.com
In humans, insulin action in the brain increases peripheral insulin sensitivity; however, the
studies demonstrating these findings were mainly performed in lean men. A new proof-of …

Das Gehirn als zentrale Schaltstelle des Stoffwechsels

J Hummel, M Heni - Die Diabetologie, 2024 - Springer
Zusammenfassung Die Untersuchung intraindividueller Unterschiede des Stoffwechsels
und des Diabetesrisikos führte zur Identifizierung von Subgruppen des Prädiabetes und …

Efficacy of Metformin Course Application Combined with Intranasal Insulin in Treating Rats with Cafeteria Diet-Induced Obesity

KV Derkach, II Zorina, AO Shpakov - Journal of Evolutionary Biochemistry …, 2024 - Springer
The so-called cafeteria diet (CD), rich in saturated fats and light fast-digesting
carbohydrates, leads to obesity and is a risk factor for type 2 diabetes. Metformin (MF) is …