Contemporary epidemiology of chronic liver disease and cirrhosis

AM Moon, AG Singal, EB Tapper - Clinical Gastroenterology and …, 2020 - Elsevier
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

A Vogel, A Cervantes, I Chau, B Daniele… - Annals of …, 2018 - annalsofoncology.org
The incidence of hepatocellular carcinoma (HCC) has been rising worldwide over the last
20 years and is expected to increase until 2030 in some countries including the United …

Changes in the global burden of chronic liver diseases from 2012 to 2017: the growing impact of NAFLD

JM Paik, P Golabi, Y Younossi, A Mishra… - Hepatology, 2020 - journals.lww.com
Conclusions Our findings indicate that LINC00665 is involved in the NF‐κB signaling
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …

Epidemiology and management of hepatocellular carcinoma

L Kulik, HB El-Serag - Gastroenterology, 2019 - Elsevier
The major risk factors for hepatocellular carcinoma (HCC) in contemporary clinical practice
are becoming increasingly related to sustained virological response after hepatitis C …

Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study

EB Tapper, ND Parikh - bmj, 2018 - bmj.com
Objective To describe liver disease related mortality in the United States during 1999-2016
by age group, sex, race, cause of liver disease, and geographic region. Design …

RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2

M Chen, L Wei, CT Law, FHC Tsang, J Shen… - Hepatology, 2018 - journals.lww.com
Epigenetic alterations have contributed greatly to human carcinogenesis. Conventional
epigenetic studies have predominantly focused on DNA methylation, histone modifications …

EASL clinical practice guidelines: management of hepatocellular carcinoma

PR Galle, A Forner, JM Llovet, V Mazzaferro… - Journal of …, 2018 - Elsevier
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

Risk factors, patterns, and outcomes of late recurrence after liver resection for hepatocellular carcinoma: a multicenter study from China

XF Xu, H Xing, J Han, ZL Li, WY Lau, YH Zhou… - JAMA …, 2019 - jamanetwork.com
Importance Late recurrence (more than 2 years) after liver resection for hepatocellular
carcinoma (HCC) is generally considered as a multicentric tumor or a de novo cancer …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …

Epidemiology of hepatocellular carcinoma and intrahepatic cholangiocarcinoma

NN Massarweh, HB El-Serag - Cancer control, 2017 - journals.sagepub.com
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most
frequently occurring types of primary liver cancer and together are among the most common …