Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus
Schistosoma. The transmission cycle requires contamination of surface water by excreta …

Schistosomes are parasitic worms that are a prime example of a complex multicellular
pathogen that flourishes in the human host despite the development of a pronounced …

Schistosomiasis continues to be a significant cause of parasitic morbidity and mortality
worldwide. This review considers the basic features of the pathology and clinical outcomes …

To dissect the controversial roles of type 1 and type 2 cytokines to the pathogenesis of
schistosomiasis, we generated IL-10/IL-4-and IL-10/IL-12-deficient mice that develop highly …

The key problem in human infectious diseases was posed at the turn of the 20th century:
their pathogenesis. For almost any given virus, bacterium, fungus, or parasite, life …

Schistosomiasis is the second most important human parasitic disease in terms of
socioeconomic impact, causing great morbidity and mortality, predominantly across the …

The clinical manifestations of schistosomiasis pass by acute, sub acute and chronic stages
that mirror the immune response to infection. The later includes in succession innate, TH1 …

In schistosomiasis mansoni, the chronic egg‐induced granulomatous response in the liver
and intestines may eventually cause extensive tissue scarring and development of portal …

The enzyme vascular non-inflammatory molecule-1 (vanin 1) is highly expressed at gene
and protein level in many organs, such as the liver, intestine, and kidney. Its major function is …

The potential impact of the Three Gorges Dam (TGD) on schistosomiasis transmission in
China has invoked considerable global concern. The TGD will result in changes in the water …