[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

The multiple roles of life stress in metabolic disorders

M Kivimäki, A Bartolomucci, I Kawachi - Nature Reviews Endocrinology, 2023 - nature.com
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis

J Cait, A Cait, RW Scott, CB Winder, GJ Mason - BMC biology, 2022 - Springer
Background Over 120 million mice and rats are used annually in research, conventionally
housed in shoebox-sized cages that restrict natural behaviours (eg nesting and burrowing) …

Social determinants of health and survival in humans and other animals

N Snyder-Mackler, JR Burger, L Gaydosh, DW Belsky… - Science, 2020 - science.org
BACKGROUND The social environment shapes human health, producing strong
relationships between social factors, disease risk, and survival. The strength of these links …

Psychosocial stress and cardiovascular disease

T Dar, A Radfar, S Abohashem, RK Pitman… - … treatment options in …, 2019 - Springer
Purpose of review This manuscript reviews the epidemiological data linking psychosocial
stress to cardiovascular disease (CVD), describes recent advances in understanding the …

[HTML][HTML] Stress-induced biological aging: A review and guide for research priorities

LR Polsky, KE Rentscher, JE Carroll - Brain, behavior, and immunity, 2022 - Elsevier
Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …

Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care

JE Carroll, JE Bower, PA Ganz - Nature Reviews Clinical Oncology, 2022 - nature.com
A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …

The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health

CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

Social ageing: exploring the drivers of late-life changes in social behaviour in mammals

ER Siracusa, JP Higham… - Biology …, 2022 - royalsocietypublishing.org
Social interactions help group-living organisms cope with socio-environmental challenges
and are central to survival and reproductive success. Recent research has shown that social …

To promote healthy aging, focus on the environment

DW Belsky, AA Baccarelli - Nature aging, 2023 - nature.com
To build health equity for an aging world marked by dramatic disparities in healthy lifespan
between countries, regions and population groups, research at the intersections of biology …