This chapter reviews the current understanding of how each of the marketed antiseizure
drugs acts on brain mechanisms to protect against seizures. Although the actions of each …

The first highly efficient, diastereo-and regioselective transition metal-catalyzed addition of
metal hydrides (stannanes, silanes, and germanes) and bimetallic species (ditins and …

The novel, chemically stabilized disorazole analog,(−)-CP 2-disorazole C 1 (1) displayed
potent anti-proliferative activity against a broad-spectrum of human colorectal cancer cells …

Design, Synthesis, and Potent Antiepileptic Activity with Latent Nerve Rehabilitation of Novel
γ-Aminobutyric Acid Derivatives Toggle navigation J-STAGE home 資料・記事を探す 資料を探す …

This paper reviews on application of two Michael reagents-ethyl
ethoxymethylenecyanoacetate (EMCA) and diethyl ethoxymethylenemalonate (DEEM …

Carbene and metal carbenoid species, originally viewed as too reactive to be useful for
complex molecule synthesis, have now emerged as attractive intermediates for the …

Since its isolation by Henri Moissan in 1886, fluorine has garnered a growing interest within
many fields of chemistry. This attention is a result of the unique properties of fluorine …

El ácido γ-aminobutiríco (GABA) es el principal neurotransmisor inhibitorio del Sistema
Nervioso Central y es sintetizado en las terminales GABAérgicas, en donde es transformado …

Most marketed antiseizure drugs were discovered by screening in animal models. Typically,
only after considerable time has passed and the drug is in widespread clinical use is its …

Peptides are crucial in biological processes: depending on their structure and location in the
body they play different important roles. In vivo, peptides can be cleaved by proteases that …