Micronuclei are small membrane-bounded compartments with a DNA content encapsulated
by a nuclear envelope and spatially separated from the primary nucleus. Micronuclei have …

Satellite DNA consists of abundant tandem repeats that play important roles in cellular
processes, including chromosome segregation, genome organization and chromosome end …

The completion of a telomere-to-telomere human reference genome, T2T-CHM13, has
resolved complex regions of the genome, including repetitive and homologous regions …

The nuclear envelope is often depicted as a static barrier that regulates access between the
nucleus and the cytosol. However, recent research has identified many conditions in …

Satellite DNAs are now regarded as powerful and active contributors to genomic and
chromosomal evolution. Paired with mobile transposable elements, these repetitive …

Micronuclei (MN), the small nucleus-like bodies separated from the primary nucleus, can
exist in cells with numerical and/or structural chromosomal aberrations in apparently normal …

Gene-environment interactions can perturb the epigenome, triggering network alterations
that participate in cancer pathogenesis. Integrating epigenomics, transcriptomics, and …

HMGA1 is an abundant non-histone chromatin protein that has been implicated in
embryonic development, cancer, and cellular senescence, but its specific role remains …

Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

The development of new technologies and experimental techniques is enabling researchers
to see what was once unable to be seen. For example, the centromere was first seen as the …