[HTML][HTML] Dissolving microneedles: Applications and growing therapeutic potential

Z Sartawi, C Blackshields, W Faisal - Journal of Controlled Release, 2022 - Elsevier
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic
compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function …

Bioinspired microneedle patches: Biomimetic designs, fabrication, and biomedical applications

P Makvandi, A Maleki, M Shabani, ARJ Hutton… - Matter, 2022 - cell.com
Nature contains abundant systems that can significantly alter their structures and properties
to adapt to the surrounding environment. Through natural selection and unceasing …

Recent advances in microneedles-based drug delivery device in the diagnosis and treatment of cancer

V Singh, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
Microneedles are unique, novel and an effective approach designed to deliver therapeutic
agents and immunobiologicals in several diseases. These tiny needle patches are designed …

Innovative transdermal drug delivery system based on amoxicillin-loaded gelatin methacryloyl microneedles obtained by 3D printing

H Erkus, T Bedir, E Kaya, GB Tinaz, O Gunduz… - Materialia, 2023 - Elsevier
The microneedle (MN) technology platform has a significant potential for enhancing the
efficacy of transdermal drug delivery, by using micron-scale arrays with restricted geometries …

Microneedle arrays combined with nanomedicine approaches for transdermal delivery of therapeutics

V Alimardani, SS Abolmaali, G Yousefi… - Journal of Clinical …, 2021 - mdpi.com
Organic and inorganic nanoparticles (NPs) have shown promising outcomes in transdermal
drug delivery. NPs can not only enhance the skin penetration of small/biomacromolecule …

Advances in microneedles research based on promoting hair regrowth

Y Zhou, L Jia, D Zhou, G Chen, Q Fu, N Li - Journal of Controlled Release, 2023 - Elsevier
Alopecia is the most common and difficult-to-treat hair disorder. It usually brings a significant
psychological burden to the patients. With the growing popularity of alopecia, the study of …

Microneedles for gene and drug delivery in skin cancer therapy

D Zhi, T Yang, T Zhang, M Yang, S Zhang… - Journal of Controlled …, 2021 - Elsevier
The success of skin cancer treatment is severely limited in the route of administration
because most genes and drugs cannot break through the excellent stratum corneum (SC) …

Microneedle-based technology for cell therapy: current status and future directions

BZ Chen, ZQ Zhao, MA Shahbazi, XD Guo - Nanoscale Horizons, 2022 - pubs.rsc.org
With the growing technological innovations in medical treatments, cell-based therapies hold
great potential as efficient tools against various previously incurable diseases by restoring or …

[HTML][HTML] pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma

Y Huang, H Lai, J Jiang, X Xu, Z Zeng, L Ren… - Asian journal of …, 2022 - Elsevier
Photodynamic therapy (PDT)-mediated oxidation treatment is extremely attractive for skin
melanoma ablation, but the strong hydrophobicity and poor tumor selectivity of …

Recent progress in microneedles‐mediated diagnosis, therapy, and theranostic systems

J Yang, J Yang, X Gong, Y Zheng, S Yi… - Advanced …, 2022 - Wiley Online Library
Theranostic system combined diagnostic and therapeutic modalities is critical for the real‐
time monitoring of disease‐related biomarkers and personalized therapy. Microneedles, as …