Fibrosis is a pathological process characterized by excessive accumulation of connective
tissue components in an organ or tissue. Fibrosis is produced by deregulated wound …

Systemic sclerosis (SSc) is a multisystem connective tissue disorder featured by vascular
injury and fibrosis of the skin and various internal organs with autoimmune background …

abstract Objectives To perform a systematic review of neurologic involvement in Systemic
sclerosis (SSc) and Localized Scleroderma (LS), describing clinical features, neuroimaging …

Systemic sclerosis (SS c) is a multisystem autoimmune disease characterized by
vasculopathy and tissue fibrosis of the skin and various internal organs. A series of genetic …

Systemic sclerosis, commonly known as scleroderma, is an autoimmune disorder
characterized by vascular abnormalities, autoimmunity, and multiorgan fibrosis. The exact …

Systemic Sclerosis (SSc) is an autoimmune disease marked by dysregulation of the immune
system, tissue fibrosis and dysfunction of the vasculature. Vascular damage, remodeling and …

Vascular endothelial growth factor (VEGF) is one of the most important inducers of
angiogenesis, therefore blocking angiogenesis has led to great promise in the treatment of …

Chronic rhinosinusitis (CRS), a common clinical condition characterized by persistent
mucosal inflammation and tissue remodeling, has a complex pathogenesis that is intricately …

Vascular disease is a hallmark of systemic sclerosis (SSc). It is present in every patient,
being responsible both for the earliest clinical manifestations and the major life-threatening …

BACKGROUND: Pulmonary hypertension (PH) is a common complication of systemic
sclerosis (SSc) and a leading cause of mortality among patients with this disease. PH can …