Plasmodium sporozoites are deposited in the skin of their vertebrate hosts through the bite
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …

Toxoplasma gondii is an obligate intracellular protozoan parasite which is a significant
human and veterinary pathogen. Other members of the phylum Apicomplexa are also …

Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …

Plasmodium sporozoite invasion of liver cells has been an extremely elusive event to study.
In the prevailing model, sporozoites enter the liver by passing through Kupffer cells, but this …

Heparin and heparan sulfate glycosaminoglycans are long, linear polysaccharides that are
made up of alternating dissacharide sequences of sulfated uronic acid and amino sugars …

Malaria infection is initiated when Anopheles mosquitoes inject Plasmodium sporozoites
into the skin. Sporozoites subsequently reach the liver, invading and developing within …

The circumsporozoite protein (CSP) is the major surface protein of Plasmodium sporozoites,
the infective stage of malaria. Although CSP has been extensively studied as a malaria …

In malaria, the red blood cell-infectious form of the Plasmodium parasite causes illness and
the possible death of infected hosts. The initial infection in the liver caused by the mosquito …