Advances in organ-on-a-chip materials and devices
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
Emerging tumor-on-chips with electrochemical biosensors
Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …
attention and interest. Advances in tissue engineering and microfluidics have led to the …
Organ-on-a-chip platforms for drug screening and delivery in tumor cells: A systematic review
IM Gonçalves, V Carvalho, RO Rodrigues, D Pinho… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
Organ-on-a-chip systems for vascular biology
Abstract Organ-on-a-chip (OOC) platforms involve the miniaturization of cell culture systems
and enable a variety of novel experimental approaches. These range from modeling the …
and enable a variety of novel experimental approaches. These range from modeling the …
Microphysiological systems evaluation: experience of TEX-VAL tissue chip testing consortium
Much has been written and said about the promise and excitement of microphysiological
systems, miniature devices that aim to recreate aspects of human physiology on a chip. The …
systems, miniature devices that aim to recreate aspects of human physiology on a chip. The …
Advances in screening hyperthermic nanomedicines in 3D tumor models
Hyperthermic nanomedicines are particularly relevant for tackling human cancer, providing
a valuable alternative to conventional therapeutics. The early-stage preclinical performance …
a valuable alternative to conventional therapeutics. The early-stage preclinical performance …
Three-dimensional vascularized lung cancer-on-a-chip with lung extracellular matrix hydrogels for in vitro screening
Simple Summary The development of three-dimensional in vitro screening tools that mimic
the microenvironment of human organs is crucial to understand the mechanism and efficacy …
the microenvironment of human organs is crucial to understand the mechanism and efficacy …
High-Throughput 3D In Vitro Tumor Vasculature Model for Real-Time Monitoring of Immune Cell Infiltration and Cytotoxicity
Recent advances in anticancer therapy have shown dramatic improvements in clinical
outcomes, and adoptive cell therapy has emerged as a type of immunotherapy that can …
outcomes, and adoptive cell therapy has emerged as a type of immunotherapy that can …
Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity
C Sakolish, HL Moyer, HHD Tsai, LC Ford… - Toxicological …, 2023 - academic.oup.com
Microphysiological systems are an emerging area of in vitro drug development, and their
independent evaluation is important for wide adoption and use. The primary goal of this …
independent evaluation is important for wide adoption and use. The primary goal of this …
Chemical and biological assessments of environmental mixtures: A review of current trends, advances, and future perspectives
Considering the chemical complexity and toxicity data gaps of environmental mixtures, most
studies evaluate the chemical risk individually. However, humans are usually exposed to a …
studies evaluate the chemical risk individually. However, humans are usually exposed to a …