Recently, we identified myeloid‐derived growth factor (MYDGF) as a blood flow‐induced
angiocrine signal that promotes human and mouse hepatocyte proliferation and survival …

Serial intravital 2-photon microscopy of the kidney and other abdominal organs is a powerful
technique to assess tissue function and structure simultaneously and over time. Thus, serial …

Introduction Despite the benefits of renin-angiotensin system (RAS) blockers, their
immediate use after nephrectomy has been limited because of concerns about impaired …

In this study, novel methods were developed, which allowed continuous (24/7)
measurement of arterial blood pressure and renal blood flow in freely moving rats and the …

Kidney disease carries significant morbidity, mortality, and cost while its prevalence is rising.
Preclinical work utilising different kidney injury models to evaluate novel therapies is a …

In the present study, novel methods were developed which allowed continuous (24/7)
measurement of blood pressure (BP) and renal blood flow (RBF) in freely moving rats and …

Background As ferroptosis is a key factor in renal fibrosis (RF), iron deposition monitoring
may help evaluating RF. The capability of quantitative susceptibility mapping (QSM) for …

Background: The compensatory changes following renal mass reduction are harmful to the
remaining kidney tissue in the long run. Therefore, they have to be controlled early. The …

The first planned clinical unilateral nephrectomy was performed by Dr. Gustav Simon in
1869. Gustav Simon, a Professor of Surgery in Heidelberg, Germany, had been treating a …

In response to the loss of functional nephrons in a kidney the remaining renal mass may
respond by undergoing one of two processes, renal atrophy, or hypertrophy. This dynamic …