During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Emerging plans for travel to Mars and other deep space destinations make it critical for us to
understand how spaceflight affects the human brain and behavior. Research over the past …

Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

Humans are exposed to extreme environmental stressors during spaceflight and return with
alterations in brain structure and shifts in intracranial fluids. To date, no studies have …

Microgravity alters vestibular signaling. In-flight adaptation to altered vestibular afferents is
reflected in post-spaceflight aftereffects, evidenced by declines in vestibularly mediated …

Astronauts returning from spaceflight typically show transient declines in mobility and
balance. Other sensorimotor behaviors and cognitive function have not been investigated as …

The environment on the space station is quite unique compared to Earth, which is a
composite of multiple stressors, such as microgravity, isolation, confinement, noise …

Abstract Space exploration objectives will soon move from low Earth orbit to distant
destinations like Moon and Mars. The present work provides an up-to-date roadmap that …

This study was designed to examine the feasibility of analyzing heart rate variability (HRV)
data from repeat-flier astronauts at matching days on two separate missions to assess any …

Although human adaptation to spaceflight has been studied for decades, little is known
about its long-term effects on brain and behavior. The present study investigated …