The many important biological functions of RNA range from propagation of genetic information to catalysis in RNA processing and protein synthesis [l]. This diverse array of …
Concomitant with our increasing knowledge of the structure and biological role of nucleic acids is the interest in the development of small molecules that can regulate DNA and RNA …
DE Draper - Journal of molecular biology, 1999 - Elsevier
Atomic resolution structures are now available for more than 20 complexes of proteins with specific RNAs. This review examines two main themes that appear in this set of structures. A …
The crystal structure of the signal sequence binding subunit of the signal recognition particle (SRP) from Thermus aquaticus reveals a deep groove bounded by a flexible loop and lined …
K Valegård, JB Murray, NJ Stonehouse… - Journal of molecular …, 1997 - Elsevier
Crystal structures of two complexes between recombinant MS2 capsids and RNA operator fragments have been determined at 2.7 Å resolution. The coat protein of the RNA …
RNA bulges constitute versatile structural motifs in the assembly of RNA architectures. Three- dimensional structures of RNA molecules and their complexes reveal the role of bulges in …
Pairing of a consensus sequence of the precursor (pre)-mRNA intron with a short region of the U2 small nuclear (sn) RNA during assembly of the eukaryotic spliceosome results in …
The iron responsive element (IRE) is a∼ 30 nucleotide RNA hairpin that is located in the 5′ untranslated region of all ferritin mRNAs and in the 3′ untranslated region of all transferrin …
E Ennifar, M Yusupov, P Walter, R Marquet… - Structure, 1999 - cell.com
Background: An important step in retroviral replication is dimerization of the genomic RNA prior to encapsidation. Dimerization is initiated by the formation of a transient 'kissing-loop …