Biological engineered living materials: growing functional materials with genetically programmable properties

C Gilbert, T Ellis - ACS synthetic biology, 2018 - ACS Publications
Natural biological materials exhibit remarkable properties: self-assembly from simple raw
materials, precise control of morphology, diverse physical and chemical properties, self …

Principles for designing synthetic microbial communities

NI Johns, T Blazejewski, ALC Gomes… - Current Opinion in …, 2016 - Elsevier
Highlights•Synthetic microbial communities have many potential uses in industrial
biotechnology.•Defined intercellular and spatiotemporal coordination enable precise …

Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

AJ Meyer, TH Segall-Shapiro, E Glassey… - Nature chemical …, 2019 - nature.com
Cellular processes are carried out by many genes, and their study and optimization requires
multiple levers by which they can be independently controlled. The most common method is …

Bacterial cellulose spheroids as building blocks for 3D and patterned living materials and for regeneration

J Caro-Astorga, KT Walker, N Herrera, KY Lee… - Nature …, 2021 - nature.com
Engineered living materials (ELMs) based on bacterial cellulose (BC) offer a promising
avenue for cheap-to-produce materials that can be programmed with genetically encoded …

De novo design of an intercellular signaling toolbox for multi-channel cell–cell communication and biological computation

P Du, H Zhao, H Zhang, R Wang, J Huang… - Nature …, 2020 - nature.com
Intercellular signaling is indispensable for single cells to form complex biological structures,
such as biofilms, tissues and organs. The genetic tools available for engineering …

Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

Y Chen, JML Ho, DL Shis, C Gupta, J Long… - Nature …, 2018 - nature.com
One challenge for synthetic biologists is the predictable tuning of genetic circuit regulatory
components to elicit desired outputs. Gene expression driven by ligand-inducible …

Turing patterns in simplicial complexes

S Gao, L Chang, M Perc, Z Wang - Physical Review E, 2023 - APS
The spontaneous emergence of patterns in nature, such as stripes and spots, can be
mathematically explained by reaction-diffusion systems. These patterns are often referred as …

Tools for engineering coordinated system behaviour in synthetic microbial consortia

N Kylilis, ZA Tuza, GB Stan, KM Polizzi - Nature communications, 2018 - nature.com
Advancing synthetic biology to the multicellular level requires the development of multiple
cell-to-cell communication channels that propagate information with minimal signal …

Synthetic biology for manipulating quorum sensing in microbial consortia

K Stephens, WE Bentley - Trends in microbiology, 2020 - cell.com
Bacteria exist as communities in diverse multispecies environments. Quorum sensing, a
process for cell–cell communication, allows individual bacteria to glean information about …

Cooperative pattern formation in multi-component bacterial systems through reciprocal motility regulation

AI Curatolo, N Zhou, Y Zhao, C Liu, A Daerr, J Tailleur… - Nature Physics, 2020 - nature.com
Self-organization is a prerequisite of biological complexity. At the population level, it
amounts to spontaneously sorting different individuals through space and time. Here, we …