1. INTRODUCTION Despite being largely absent from natural products and biological
processes, fluorine plays a conspicuous and increasingly important role within …

Fluorine, often called as “a small atom with a big ego”, 1 lies in the second row and the 17th
column in the periodic table of the chemical elements. This unique position in the periodic …

Sulfones are flexible functional groups that can act as nucleophiles, electrophiles, or even
radicals. Changing the reaction conditions can completely alter the reactivity of a sulfonyl …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

The development of new asymmetric methodologies that afford different structures in an
enantioselective fashion is one of the most exciting goals for chemists nowadays. In this …

Asymmetric organocatalysis has become a powerful tool for the synthesis of optically active
compounds. Whereas early research mainly focused on combining simple reagents as a …

Recent years have witnessed an explosive growth in the field of amino organocatalysis,
especially in asymmetric enamine and iminium catalysis. Except for the obvious interaction …

The enantioselective synthesis of fluorinated molecules has drawn much attention within the
chemical community due to its unique stereoelectronic properties. The main aim of this …

A highly enantio-and regio-selective Markovnikov hydromonofluoro (methyl) alkylation of 1,
3-dienes was developed using redox-neutral nickel catalysis. It provided a facile strategy to …

Ammonium salts are used as phase-transfer catalysts for fluorination with alkali metal
fluorides. We now demonstrate that these organic salts, specifically azetidinium triflates, are …