Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of
cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85 …

The multiple roles played by RNA binding proteins in neurodegeneration have become
apparent following the discovery of TAR DNA binding protein 43 kDa (TDP‐43) and fused in …

The findings that amyotrophic lateral sclerosis (ALS) patients almost universally display
pathological mislocalization of the RNA-binding protein TDP-43 and that mutations in its …

Interest in cancer metabolism has increased in recent years. The pentose phosphate
pathway (PPP) is a major glucose catabolism pathway that directs glucose flux to its …

Background: Hepatocellular carcinoma (HCC) is a malignant tumor associated with high
morbidity and mortality. Therefore, it is of great importance to develop effective prognostic …

Abstract Phosphofructokinase-1 (PFK1), the 'gatekeeper'of glycolysis, catalyses the
committed step of the glycolytic pathway by converting fructose-6-phosphate to fructose-1, 6 …

Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic
pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic …

Hepatocellular carcinoma (HCC) is one of the most lethal cancers, and its rate of incidence
is rising annually. Despite the progress in diagnosis and treatment, the overall prognoses of …

Background Vascular invasion is a major route for intrahepatic and distant metastasis in
hepatocellular carcinoma (HCC) and is a strong negative prognostic factor. Circular RNAs …

Hepatocellular carcinoma (HCC) metabolism is redirected to glycolysis to enhance the
production of metabolic compounds employed by cancer cells to produce proteins, lipids …