[HTML][HTML] What is the difference between IgA nephropathy and Henoch-Schönlein purpura nephritis?

JC Davin, IJ Ten Berge, JJ Weening - Kidney international, 2001 - Elsevier
What is the difference between IgA nephropathy and Henoch-Schönlein purpura nephritis?
Henoch-Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are considered to …

Pathogenesis of IgA nephropathy

J Barratt, J Feehally, AC Smith - Seminars in nephrology, 2004 - Elsevier
In IgA nephropathy (IgAN), there is dysregulation of the IgA response to a wide range of
antigens. The dysregulation promotes synthesis of polymeric IgA1 (pIgA1) with …

The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function for IgA.

CS Kaetzel, JK Robinson… - Proceedings of the …, 1991 - National Acad Sciences
The polymeric immunoglobulin receptor (pIgR) on mucosal epithelial cells binds dimeric IgA
(dIgA) on the basolateral surface and mediates transport of dIgA to the apical surface. Using …

Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG

M Tomana, K Matousovic, BA Julian, J Radl… - Kidney international, 1997 - Elsevier
Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with
IgG. IgA1 proteins from sera of patients with IgA nephropathy (IgAN) are galactosylated to a …

Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy

J Mestecky, M Tomana… - Contributions to …, 1993 - books.google.com
Elevated plasma levels of IgA1, IgA1-rheumatoid factor (RF), and IgA1-containing immune
complexes (IgA1-IC) have been detected in patients with a broad spectrum of diseases …

The N-Glycans Determine the Differential Blood Clearance and Hepatic Uptake of Human Immunoglobulin (Ig)a1 and Iga2 Isotypes

A Rifai, K Fadden, SL Morrison… - The Journal of …, 2000 - rupress.org
Human immunoglobulin (Ig) A exists in blood as two isotypes, IgA1 and IgA2, with IgA2
present as three allotypes: IgA2m (1), IgA2m (2), and IgA2m (n). We now demonstrate that …

Cohort study of advanced IgA nephropathy: efficacy and limitations of corticosteroids with tonsillectomy

M Sato, O Hotta, S Tomioka, I Horigome… - Nephron Clinical …, 2003 - karger.com
Background: Elevated serum creatinine is associated with poor outcome in IgA nephropathy
(IgAN). The efficacy and limitations of corticosteroids in advanced IgAN (Cr≧ 1.5 mg/dl) …

Immunopathogenesis of IgAN

J Barratt, AC Smith, K Molyneux, J Feehally - Seminars in …, 2007 - Springer
The defining hallmark of IgA nephropathy (IgAN) is deposition of polymeric IgA1 in the
glomerular mesangium accompanied by a mesangial proliferative glomerulonephritis. The …

Immunoregulatory factors in the pathogenesis of IgA nephropathy

JJ COHEN, JT HARRINOTON, JP KASSIRER… - Kidney international, 1990 - Elsevier
Discussion DR. STEVEN N. EMANCIPATOR (Pathologist, University Hos-pitals of
Cleveland, and Associate Professor of Pathology, Case Western Reserve University School …

[HTML][HTML] Bone marrow transplantation attenuates murine IgA nephropathy: role of a stem cell disorder

T Imasawa, R Nagasawa, Y Utsunomiya… - Kidney international, 1999 - Elsevier
Bone marrow transplantation attenuates murine IgA nephropathy: Role of a stem cell
disorder. Background The pathogenesis of IgA nephropathy is still obscure. The aim of this …