Exploring the interaction between extracellular matrix components in a 3D organoid disease model to replicate the pathophysiology of breast cancer
A Bhattacharya, K Alam, NS Roy, K Kaur… - Journal of Experimental …, 2023 - Springer
In vitro models are necessary to study the pathophysiology of the disease and the
development of effective, tailored treatment methods owing to the complexity and …
development of effective, tailored treatment methods owing to the complexity and …
Multi compartmental 3D breast cancer disease model–recapitulating tumor complexity in in-vitro
Breast cancer is the most common ailment among women. In 2020, it had the highest
incidence of any type of cancer. Many Phase II and III anti-cancer drugs fail due to efficacy …
incidence of any type of cancer. Many Phase II and III anti-cancer drugs fail due to efficacy …
Bioprinting of 3D breast epithelial spheroids for human cancer models
Abstract 3D human cancer models provide a better platform for drug efficacy studies than
conventional 2D culture, since they recapitulate important aspects of the in vivo …
conventional 2D culture, since they recapitulate important aspects of the in vivo …
Advancing Bioactive Material for Mandibular Bone Regeneration: Transformation of Fibrous Mat into 3D Matrix Cotton for Enhanced Shape Retention and Rapid …
S Thomas, AR Rajendran… - ACS Biomaterials …, 2024 - ACS Publications
Transformation of a fibrous mat into a three-dimensional (3D) scaffold opens up abundant
innovative prospects in biomedical research, particularly for studying both soft as well as …
innovative prospects in biomedical research, particularly for studying both soft as well as …
A New Approach to Inhibiting Triple-Negative Breast Cancer: In Vitro, Ex Vivo and In Vivo Antiangiogenic Effect of BthTx-II, a PLA2-Asp-49 from Bothrops jararacussu …
F Van Petten de Vasconcelos Azevedo, DS Lopes… - Biomolecules, 2022 - mdpi.com
Phospholipases A2 (PLA2) represent a superfamily of enzymes widely distributed in living
organisms, with a broad spectrum of pharmacological activities and therapeutic potential …
organisms, with a broad spectrum of pharmacological activities and therapeutic potential …
A microfluidic mammary gland coculture model using parallel 3D lumens for studying epithelial-endothelial migration in breast cancer
In breast cancer development, crosstalk between mammary epithelial cells and neighboring
vascular endothelial cells is critical to understanding tumor progression and metastasis, but …
vascular endothelial cells is critical to understanding tumor progression and metastasis, but …
Pollonein-LAAO unveiling anti-angiogenic effects through oxidative stress: Insights from mimetic tumor angiogenesis environment in a 3D co-culture model
L Polloni, TR Costa, LP Morais, BC Borges… - Chemico-Biological …, 2025 - Elsevier
Tumor angiogenesis is a multistep process of new and abnormal blood vessels network
formation from a pre-existing vasculature [1, 2]. On account of its fundamental role in tumor …
formation from a pre-existing vasculature [1, 2]. On account of its fundamental role in tumor …
Direct bioprinting of 3D multicellular breast spheroids onto endothelial networks
S Swaminathan, AM Clyne - Journal of visualized experiments …, 2020 - pmc.ncbi.nlm.nih.gov
Bioprinting is emerging as a promising tool to fabricate 3D human cancer models that better
recapitulate critical hallmarks of in vivo tissue architecture. In current layer-by-layer extrusion …
recapitulate critical hallmarks of in vivo tissue architecture. In current layer-by-layer extrusion …
Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles
Abstract Background Cancer stem cells (CSCs) are a subpopulation of cancer cells that are
believed to be responsible for tumor initiation, progression, metastasis, and resistance to …
believed to be responsible for tumor initiation, progression, metastasis, and resistance to …
A Three-Dimensional In Vitro Coculture Model to Quantify Breast Epithelial Cell Adhesion to Endothelial Cells
S Swaminathan, AN Cranston… - Tissue Engineering Part C …, 2019 - liebertpub.com
Three-dimensional (3D) in vitro culture models better recapitulate the tissue
microenvironment, and therefore may provide a better platform to evaluate therapeutic …
microenvironment, and therefore may provide a better platform to evaluate therapeutic …