Antitumoral activity of quinoxaline derivatives: A systematic review

M Montana, F Mathias, T Terme, P Vanelle - European journal of medicinal …, 2019 - Elsevier
Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, the majority of drugs currently on the market are …

The chemistry of heterocycles in the 21st century

VN Charushin, EV Verbitskiy, ON Chupakhin… - Uspekhi Khimii, 2024 - mathnet.ru
The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

Recent advances in the transition-metal-free synthesis of quinoxalines

B Borah, LR Chowhan - RSC advances, 2021 - pubs.rsc.org
Quinoxalines, also known as benzo [a] pyrazines, constitute an important class of nitrogen-
containing heterocyclic compounds as a result of their widespread prevalence in natural …

Living on pyrrolic foundations–Advances in natural and artificial bioactive pyrrole derivatives

A Domagala, T Jarosz, M Lapkowski - European journal of medicinal …, 2015 - Elsevier
Pyrrole, a simple heterocyclic system, is an important building block for numerous
biologically active compounds both natural and synthetic in origin, which boast an immense …

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

ES Tantawy, AM Amer, EK Mohamed… - Journal of Molecular …, 2020 - Elsevier
In continuation of our interest on the synthesis of fused quinoxalines and pyrazines
derivatives and due to the resultant pharmacological interest in compounds which belong to …

Dimethyl sulfoxide involved one-pot synthesis of quinoxaline derivatives

C Xie, Z Zhang, D Li, J Gong, X Han… - The Journal of organic …, 2017 - ACS Publications
An efficient, green, and novel method for the synthesis of N-heterocycle-fused quinoxalines
is reported herein. Dimethyl sulfoxide was used as both a reactant and a solvent in this …

Quinoxaline derivatives as a promising scaffold for breast cancer treatment

RRE Eldin, AA Al-Karmalawy, MH Alotaibi… - New Journal of …, 2022 - pubs.rsc.org
According to Global Cancer Statistics 2021, female breast cancer has exceeded lung cancer
as the most frequently diagnosed cancer. As a result of this widespread breast cancer, it is …

Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives

J Guillon, A Cohen, NM Gueddouda… - Journal of enzyme …, 2017 - Taylor & Francis
Novel series of bis-and tris-pyrrolo [1, 2-a] quinoxaline derivatives 1 were synthesized and
tested for in vitro activity upon the intraerythrocytic stage of W2 and 3D7 Plasmodium …

New achievements in the synthesis of pyrrolo[1,2-a]quinoxalines

AA Kalinin, LN Islamova, GM Fazleeva - Chemistry of Heterocyclic …, 2019 - Springer
This review article describes methods for the preparation of pyrrolo [1, 2-a] quinoxalines,
covering literature sources from the last 10 years. The attention was largely paid to new …

NCS-promoted thiocyanation and selenocyanation of pyrrolo [1, 2-a] quinoxalines

Z Yang, J He, Y Wei, W Li, P Liu, J Zhao… - Organic & Biomolecular …, 2020 - pubs.rsc.org
An efficient NCS-promoted thiocyanation of pyrrolo [1, 2-a] quinoxalines with NH4SCN or
KSCN is described. A series of diverse 1-thiocyanatopyrrolo [1, 2-a] quinoxalines were …