Nanomedicine is a discipline that applies nanoscience and nanotechnology principles to the
prevention, diagnosis, and treatment of human diseases. Self-assembly of molecular …

The safety of anesthesia has improved greatly in the past three decades. Standard
perioperative monitoring, including pulse oximetry, has practically eliminated unrecognized …

Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in
this prospective study the effect of rewarming rate on neurocognitive outcome after …

Background—Near-infrared spectroscopy monitoring of cerebral oxygen saturation (rSo2)
has become routine in many centers, but no studies have reported the relationship of …

Objectives Neonates with hypoplastic left heart syndrome have significant hemodynamic
threats to cerebral perfusion and are at risk of reduced neurodevelopmental performance …

Background Jugular venous hemoglobin desaturation during the rewarming phase of
cardiopulmonary bypass is associated with adverse neuropsychologic outcome and may …

The neonatal brain is extremely vulnerable to injury during periods of hypoxia and/or
ischemia. Risk of brain injury is increased during neonatal cardiac surgery, where pre …

Objectives: Near-infrared spectrophotometry (NIRS) is a promising method for non-invasive
monitoring of cerebral oxygenation and hemodynamics. This paper reviews studies in which …

Acute perioperative anaemia may affect neurological injury from permanent focal ischaemic
insults. We modelled the opposing effects of haemodilution (increasing cerebral blood flow …

Objectives To evaluate jugular venous oxygen saturation (SjvO 2), measured with a
fiberoptic oximetry catheter, and brain tissue oxygen saturation, measured by near-infrared …