UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

A systematic revision of the literature was conducted in order to undertake a comprehensive
meta-analysis of all published observational studies on melanoma. An extensive analysis of …

A systematic meta-analysis of observational studies of melanoma and family history, actinic
damage and phenotypic factors was conducted as part of a comprehensive meta-analysis of …

Skin cancers, predominantly basal-cell and squamous-cell carcinomas, have accounted for
an estimated 40 percent of all cancers in the United States in recent years, and their …

To assess the association between the incidence of cutaneous melanoma; intermittent,
occupational and total sun exposure; and history of sunburn at different ages, we conducted …

The RAS/mitogen-activated protein kinase pathway sends external growth-promoting
signals to the nucleus. BRAF, a critical serine/threonine kinase in this pathway, is frequently …

This review article outlines the physical, chemical, biological, ergonomic and psychosocial
occupational health hazards of mining and associated metallurgical processes. Mining …

PURPOSE: Sunburns are an important risk factor for melanoma and those occurring in
childhood are often cited as posing the greatest risk. We conducted a meta-analysis to …

The incidence and mortality rates of melanoma have risen for many decades in the United
States. Increased exposure to ultraviolet (UV) radiation is generally considered to be …

Background: As skin cancer education programmes directed to children and adolescents
continue to expand, an epidemiological basis for these programmes is necessary to target …