V Kovaleva, LY Yu, L Ivanova, O Shpironok, J Nam… - Cell Reports, 2023 - cell.com
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-located protein with cytoprotective effects in neurons and pancreatic β cells in vitro and …
The conserved mesencephalic astrocyte-derived neurotrophic factor (MANF) is known for protecting dopaminergic neurons and functioning in various other tissues. Previously, we …
T Danilova, E Galli, E Pakarinen, E Palm… - Frontiers in …, 2019 - frontiersin.org
Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) form a family of atypical growth factors discovered for their …
H Lõhelaid, JE Anttila, HK Liew, KY Tseng… - Frontiers in Cellular …, 2022 - frontiersin.org
Stroke is a devastating medical condition with no treatment to hasten recovery. Its abrupt nature results in cataclysmic changes in the affected tissues. Resident cells fail to cope with …
E Pakarinen, P Lindholm - Frontiers in psychiatry, 2023 - frontiersin.org
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical …
J Teppo, A Vaikkinen, V Stratoulias, K Mätlik… - Experimental …, 2020 - Elsevier
The peri-infarct region after ischemic stroke is the anatomical location for many of the endogenous recovery processes; however,-the molecular events in the peri-infarct region …
J Fu, KM Nchambi, H Wu, X Luo, X An, D Liu - Life sciences, 2020 - Elsevier
Aims This study was conducted to determine the relationship between mesencephalic astrocyte-derived neurotrophic factor (MANF), autophagy and endoplasmic reticulum (ER) …
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) localized protein that regulates ER homeostasis and unfolded protein response (UPR) …