Perspectives of diabetic retinopathy—challenges and opportunities

S Sivaprasad, S Sen, J Cunha-Vaz - Eye, 2023 - nature.com
Diabetic retinopathy (DR) may lead to vision-threatening complications in people living with
diabetes mellitus. Decades of research have contributed to our understanding of the …

[HTML][HTML] Variations in Electronic Health Record-based Definitions of Diabetic Retinopathy Cohorts: A Literature Review and Quantitative Analysis

JS Chen, IA Copado, C Vallejos, FGP Kalaw… - Ophthalmology …, 2024 - Elsevier
Purpose Use of the electronic health record (EHR) has motivated the need for data
standardization. A gap in knowledge exists regarding variations in existing terminologies for …

Identification of the relationship between hub genes and immune cell infiltration in vascular endothelial cells of proliferative diabetic retinopathy using bioinformatics …

J Huang, Q Zhou - Disease Markers, 2022 - Wiley Online Library
Background. Diabetic retinopathy (DR) is a serious ophthalmopathy that causes blindness,
especially in the proliferative stage. However, the pathogenesis of its effect on endothelial …

Prediction of diabetic retinopathy using health records with machine learning classifiers and data science

B Sumathy, A Chakrabarty, S Gupta… - International Journal of …, 2022 - igi-global.com
Diabetes is a rapidly spreading disease. When the pancreas produces insufficient insulin or
the body cannot utilise it effectively. Diabetic Retinopathy (DR) and blindness are two major …

Novel therapies for proliferative retinopathies

JM Martinez-Alejo, LM Baiza-Duran… - … in Chronic Disease, 2022 - journals.sagepub.com
Proliferative retinopathies, such as neovascular age–related macular degeneration and
proliferative diabetic retinopathy, are a special health issue due to their contribution to …

Injectable hydrogels based on biopolymers for the treatment of ocular diseases

C Yu, J Xu, G Heidari, H Jiang, Y Shi, A Wu… - International Journal of …, 2024 - Elsevier
Injectable hydrogels based on biopolymers, fabricated utilizing diverse chemical and
physical methodologies, exhibit exceptional physical, chemical, and biological properties …

[HTML][HTML] A caveat about financial incentives for anti-vascular endothelial growth factor therapy for diabetic retinopathy

BK Young, M Hwang, MW Johnson, CG Besirli… - American journal of …, 2022 - Elsevier
Purpose To highlight the financial incentive to the physician of choosing an intravitreal anti-
vascular endothelial growth factor (VEGF)-based strategy for treating non-proliferative and …

[PDF][PDF] Ocular Complications Associated with Diabetes and The Risk of Sustainable Blindness; A Real World Analysis

T Mahmood, MF Fahim, S Ahsan, U Qidwai… - J Pak Med …, 2023 - academia.edu
Objective: To evaluate the frequencies of ocular comorbidities among patients with type II
diabetes, and the association with multiple systemic factors. Method: The retrospective …

[HTML][HTML] Circulating biomarkers of inflammation and endothelial activation in diabetic retinopathy

F Storti, J Pulley, P Kuner, M Abt… - … vision science & …, 2021 - iovs.arvojournals.org
Inflammation and endothelial activation play a pivotal role in development and progression
of diabetic retinopathy (DR), a vision-threatening complication of diabetes mellitus (DM) and …

ROBIN: a randomised, double-masked, placebo-controlled Phase IIa study of the AOC3 inhibitor BI 1467335 in diabetic retinopathy

Q Dong Nguyen, JP Ehlers, DS Boyer, X Jin, A Giani… - Eye, 2024 - nature.com
Objective To evaluate the safety and efficacy of BI 1467335 in patients with non-proliferative
diabetic retinopathy (NPDR). Methods ROBIN is a Phase IIa, double-masked, randomised …