Propofol is an intravenous agent used commonly for the induction and maintenance of
anesthesia, procedural, and critical care sedation in children. The mechanisms of action on …

Lidocaine is an amide local anaesthetic initially used intravenously as an antiarrhythmic
agent. At some point it was proposed that intravenous lidocaine (IVL) had an analgesic …

Ciprofol is a propofol analogue with improved pharmacokinetic properties. A multi‐centre,
non‐inferiority trial was conducted to compare the deep sedation properties of ciprofol and …

Ciprofol is a novel compound that was independently developed in China. According to the
Chinese product instructions approved by the China National Medical Products …

OBJECTIVE: Ciprofol is a newly developed intravenous sedative-hypnotic drug. The
objective of the study was to prove whether ciprofol was non-inferior to propofol for the …

Introduction The effects of continuous infusions of ciprofol on its pharmacodynamic and
pharmacokinetic properties and safety profiles in healthy Chinese subjects were evaluated …

Background: Ranking of interventions is one of the most appealing elements of network
meta-analysis. There is, however, little evidence about the reliability of these rankings …

Propofol administered in conjunction with an opioid such as remifentanil is used to provide
total intravenous anesthesia for children. Drugs can be given as infusion controlled …

Background Ciprofol is a recently developed, short-acting γ-aminobutyric acid receptor
agonist sedative that is more potent than propofol, but there have been few clinical studies of …

Pain on propofol injection (POPI) is a minor problem that all anesthetists face every day.
Introduction of several new formulations and hundreds of clinical trials have failed to find its …