Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Multicomponent solid forms of low molecular weight drugs, such as co-crystals, salts, and co-
amorphous systems, are a result of the combination of an active pharmaceutical ingredient …

Almost half of orally administered active pharmaceutical ingredients (APIs) have low
solubility, which affects their bioavailability. In the last two decades, several alternatives …

In this work, the cocrystallization approach was applied to itraconazole (ITR), a very slightly
soluble triazole antifungal drug, which led to the formation of two new solid forms of ITR with …

Experimental and theoretical screening of multi-component crystal forms of miconazole
(MCL), an antifungal drug, with ten aliphatic dicarboxylic acids was performed. Seven multi …

The study presents a thorough and detailed analysis of bicalutamide's structural and
conformational properties. Quantum chemical calculations were employed to explore the …

Pharmaceutical cocrystals, an important multi-component complex compressing at least two
molecules linked by noncovalent bonds within the same crystal lattice, have shown a great …

Emerging evidence suggests that intestinal permeability can be potentially enhanced
through cocrystallization. However, a mechanism for this effect remains to be established. In …

Periodic density-functional theory (DFT) calculations were used to predict the
thermodynamic stability and the likelihood of interconversion between a series of halogen …

2, 4-Dichlorophenoxyacetic acid (2, 4-D) is an herbicide and plant growth regulator that is
widely applied in crop production. New multicomponent crystals of 2, 4-D have been …