[HTML][HTML] Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence

L Wang, Y Wang, D Ye, Q Liu - International journal of antimicrobial agents, 2020 - Elsevier
COVID-19, the disease caused by SARS-CoV-2, is a highly contagious disease. The World
Health Organization has declared the ongoing outbreak to be a global public health …

Potential interventions for novel coronavirus in China: A systematic review

L Zhang, Y Liu - Journal of medical virology, 2020 - Wiley Online Library
An outbreak of a novel coronavirus (COVID‐19 or 2019‐CoV) infection has posed significant
threats to international health and the economy. In the absence of treatment for this virus …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): a clinical update

M Zhou, X Zhang, J Qu - Frontiers of medicine, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. It …

Middle East respiratory syndrome

ZA Memish, S Perlman, MD Van Kerkhove, A Zumla - The Lancet, 2020 - thelancet.com
Summary The Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal
zoonotic pathogen that was first identified in humans in Saudi Arabia and Jordan in 2012 …

[HTML][HTML] Overview of lethal human coronaviruses

B Chen, EK Tian, B He, L Tian, R Han… - Signal transduction and …, 2020 - nature.com
Coronavirus infections of multiple origins have spread to date worldwide, causing severe
respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV …

[HTML][HTML] Artificial intelligence for COVID-19 drug discovery and vaccine development

A Keshavarzi Arshadi, J Webb, M Salem… - Frontiers in Artificial …, 2020 - frontiersin.org
SARS-COV-2 has roused the scientific community with a call to action to combat the growing
pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved …

[HTML][HTML] Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19

Y Xie, S Cao, H Dong, Q Li, E Chen, W Zhang… - The Journal of …, 2020 - ncbi.nlm.nih.gov
As discussed in the Journal recently1 the SARS-CoV-2, a new β-Coronavirus, uses the
Angiotensin Converting Enzyme-2 Receptor to enter airway cells. Viral endocytosis is …

Antimicrobial peptides–Advances in development of therapeutic applications

HX Luong, TT Thanh, TH Tran - Life sciences, 2020 - Elsevier
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …

The development of Coronavirus 3C-Like protease (3CLpro) inhibitors from 2010 to 2020

Y Liu, C Liang, L Xin, X Ren, L Tian, X Ju, H Li… - European journal of …, 2020 - Elsevier
This review fully describes the coronavirus 3CL pro peptidomimetic inhibitors and
nonpeptidic small molecule inhibitors developed from 2010 to 2020. Specifically, the …