[HTML][HTML] Routine omics collection is a golden opportunity for European human research in space and analog environments

H Cope, CRG Willis, MJ MacKay, LA Rutter, LS Toh… - Patterns, 2022 - cell.com
Widespread generation and analysis of omics data have revolutionized molecular medicine
on Earth, yet its power to yield new mechanistic insights and improve occupational health …

[HTML][HTML] Role of miR-2392 in driving SARS-CoV-2 infection

JT McDonald, FJ Enguita, D Taylor, RJ Griffin, W Priebe… - Cell reports, 2021 - cell.com
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene
regulation that have a major impact on many diseases and provide an exciting avenue …

Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments

A Manzano, E Carnero-Diaz, R Herranz, FJ Medina - Iscience, 2022 - cell.com
Discovering the adaptation mechanisms of plants to the space environment is essential for
supporting human space exploration. Transcriptomic analyses allow the identification of …

Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses

K Grigorev, TM Nelson, EG Overbey, N Houerbi… - Nature …, 2024 - nature.com
The advent of civilian spaceflight challenges scientists to precisely describe the effects of
spaceflight on human physiology, particularly at the molecular and cellular level. Newer …

[HTML][HTML] Epstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms

A Casco, M Ohashi, E Johannsen - Cell reports, 2024 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous oncogenic virus associated with multiple cancers
and autoimmune diseases. Unlike most herpesviruses, EBV reactivation from latency occurs …

Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology

H Cope, J Elsborg, S Demharter, JT McDonald… - Communications …, 2024 - nature.com
Background Spaceflight poses a unique set of challenges to humans and the hostile
spaceflight environment can induce a wide range of increased health risks, including …

NASA open science data repository: open science for life in space

SG Gebre, RT Scott, AM Saravia-Butler… - Nucleic Acids …, 2025 - academic.oup.com
Abstract Space biology and health data are critical for the success of deep space missions
and sustainable human presence off-world. At the core of effectively managing biomedical …

[HTML][HTML] Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster

SD Mhatre, J Iyer, J Petereit, RM Dolling-Boreham… - Cell reports, 2022 - cell.com
Spaceflight poses risks to the central nervous system (CNS), and understanding
neurological responses is important for future missions. We report CNS changes in …

Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice

K Li, R Desai, RT Scott, JR Steele, M Machado… - npj …, 2023 - nature.com
The adverse effects of microgravity exposure on mammalian physiology during spaceflight
necessitate a deep understanding of the underlying mechanisms to develop effective …

To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants

G Corti, JK Kim, FJ Enguita, JW Guarnieri… - Communications …, 2024 - nature.com
In the era of renewed space exploration, comprehending the effects of the space
environment on human health, particularly for deep space missions, is crucial. While …