Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Recent studies using cell type–specific knockout mouse models have improved our
understanding of the pathophysiological relevance of suppressor of lin-12-like–HMG-CoA …

Exosomes are a new means of intercellular information exchange that have aroused great
research interest. Long neglected in research, exosomes were deemed nonfunctional …

Tumor progression involves invasion, migration, metabolism, autophagy, exosome
secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie …

Insulin receptor (INSR) has been extensively studied in the area of cell proliferation and
energy metabolism. Impaired INSR activities lead to insulin resistance, the key factor in the …

EV (extracellular vesicle) biology is a rapidly expanding field. These heterogeneous
membrane vesicles, which are shed from virtually all cell types, collectively represent a new …

The endosomal system orchestrates the transport of lipids, proteins and nutrients across the
entire cell. Along their journey, endosomes mature, change shape via fusion and fission …

Extracellular vesicles (EVs) mediate the cross‐talk between cancer cells and the cells of the
surrounding Tumour Microenvironment (TME). Professional killer cells include Natural Killer …

Extracellular vesicles (EVs) are complex biological nanoparticles endogenously secreted by
all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids …