Within the past decade, multiple lines of evidence have converged to identify a critical role
for activity-regulated myelination in tuning the function of neural networks. In this Review, we …

During cortical development and throughout adulthood, oligodendrocytes add myelin
internodes to glutamatergic projection neurons and GABAergic inhibitory neurons. In …

Accumulation of reactive oxygen species (ROS), especially on lipids, induces massive cell
death in neurons and oligodendrocyte progenitor cells (OPCs) and causes severe …

Importance Elevated maternal psychological distress during pregnancy is associated with
altered fetal brain development. During the COVID-19 pandemic, prenatal maternal …

Fear generalization is a neurobiological process by which an organism interprets a novel
stimulus as threatening because of its similarity to previously learned fear-inducing stimuli …

Early adversity (EA) impairs myelin development in a manner that persists later in life across
diverse mammalian species including humans, non-human primates, and rodents. These …

Stress disorders are leading causes of disease burden in the US and worldwide, yet
available therapies are fully effective in less than half of all individuals with these disorders …

Abstract Cross-sectional Diffusion Tensor Imaging (DTI) studies have reported alterations in
white matter (WM) microstructure in adolescents with internalizing psychopathology. Yet …

Objective We aim to investigate the interplay between mentalization, brain microstructure,
and psychological resilience as potential protective factors against mental illness. Method …

Anxiety and fear are dysfunctional behaviors commonly observed in domesticated dogs.
Although dogs and humans share psychopathological similarities, little is known about how …