Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Curcumin supplementation and human disease: a scoping review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …

DNA methylation and schizophrenia: current literature and future perspective

T Magwai, KB Shangase, FO Oginga, B Chiliza… - Cells, 2021 - mdpi.com
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

Curcumin nanoformulations to combat aging-related diseases

M Mahjoob, U Stochaj - Ageing Research Reviews, 2021 - Elsevier
Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

Current clinical developments in curcumin‐based therapeutics for cancer and chronic diseases

A Kumar, C Harsha, D Parama, S Girisa… - Phytotherapy …, 2021 - Wiley Online Library
The last decade has seen an unprecedented rise in the prevalence of chronic diseases
worldwide. Different mono‐targeted approaches have been devised to treat these multigenic …

The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway

D Namgyal, S Ali, R Mehta, M Sarwat - Toxicology, 2020 - Elsevier
Heavy metal neurotoxicity is one of the major challenges in today's era due to the large
scale and widespread mechanisation of the production. However, the causative factors …

Curcumin intervention for cognitive function in different types of people: A systematic review and meta‐analysis

LN Zhu, X Mei, ZG Zhang, Y Xie… - Phytotherapy …, 2019 - Wiley Online Library
Curcumin is a polyphenolic natural compound with diverse and attractive biological
activities, which may prevent or ameliorate pathological processes underlying age‐related …

Hormetic Nutrition and Redox Regulation in Gut–Brain Axis Disorders

M Scuto, F Rampulla, GM Reali, SM Spanò… - Antioxidants, 2024 - mdpi.com
The antioxidant and anti-inflammatory effects of hormetic nutrition for enhancing stress
resilience and overall human health have received much attention. Recently, the gut–brain …

The effect of curcumin differs on individual cognitive domains across different patient populations: a systematic review and meta-analysis

IC Tsai, CW Hsu, CH Chang, PT Tseng, KV Chang - Pharmaceuticals, 2021 - mdpi.com
Curcumin is a polyphenol with strong antioxidant and anti-inflammatory effects that has been
shown to be effective in ameliorating cognitive decline in animal studies. However, its …

An update on the exploratory use of curcumin in neuropsychiatric disorders

N Lamanna-Rama, D Romero-Miguel, M Desco… - Antioxidants, 2022 - mdpi.com
Curcumin is a polyphenol extracted from the rhizome of the turmeric plant. Beyond its
common use as a culinary spice in Eastern Asia, curcumin has been proposed as a …