[HTML][HTML] Machine learning and data mining methods in diabetes research

I Kavakiotis, O Tsave, A Salifoglou… - Computational and …, 2017 - Elsevier
The remarkable advances in biotechnology and health sciences have led to a significant
production of data, such as high throughput genetic data and clinical information, generated …

Machine learning techniques for personalised medicine approaches in immune-mediated chronic inflammatory diseases: applications and challenges

J Peng, EC Jury, P Dönnes, C Ciurtin - Frontiers in pharmacology, 2021 - frontiersin.org
In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine

S Hagan, E Martin, A Enríquez-de-Salamanca - Epma Journal, 2016 - Springer
In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

[HTML][HTML] Biomarkers in diabetic retinopathy

AJ Jenkins, MV Joglekar, AA Hardikar… - The review of diabetic …, 2015 - ncbi.nlm.nih.gov
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Proteomic biomarkers of retinal inflammation in diabetic retinopathy

H Youngblood, R Robinson, A Sharma… - International journal of …, 2019 - mdpi.com
Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …

Mass spectrometry‐based tear proteomics for noninvasive biomarker discovery

E Ponzini, C Santambrogio, A De Palma… - Mass Spectrometry …, 2022 - Wiley Online Library
The lacrimal film has attracted increasing interest in the last decades as a potential source of
biomarkers of physiopathological states, due to its accessibility, moderate complexity, and …

Metabolomics of various samples advancing biomarker discovery and pathogenesis elucidation for diabetic retinopathy

X Du, L Yang, L Kong, Y Sun, K Shen, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus
(DM), which is the main reason for global sight damage/loss in middle-aged and/or older …

Putative biomarkers in tears for diabetic retinopathy diagnosis

M Amorim, B Martins, F Caramelo, C Gonçalves… - Frontiers in …, 2022 - frontiersin.org
Purpose Tear fluid biomarkers may offer a non-invasive strategy for detecting diabetic
patients with increased risk of developing diabetic retinopathy (DR) or increased disease …

Unraveling the molecular repertoire of tears as a source of biomarkers: beyond ocular diseases

D Pieragostino, M D'Alessandro… - Proteomics–Clinical …, 2015 - Wiley Online Library
Proteomics and metabolomics investigations of body fluids present several challenges for
biomarker discovery of several diseases. The search for biomarkers is actually conducted in …

[HTML][HTML] A review on automatic analysis techniques for color fundus photographs

R Besenczi, J Tóth, A Hajdu - Computational and structural biotechnology …, 2016 - Elsevier
In this paper, we give a review on automatic image processing tools to recognize diseases
causing specific distortions in the human retina. After a brief summary of the biology of the …