Ice inhibition for cryopreservation: materials, strategies, and challenges

T Chang, G Zhao - Advanced Science, 2021 - Wiley Online Library
Cryopreservation technology has developed into a fundamental and important supporting
method for biomedical applications such as cell‐based therapeutics, tissue engineering …

Bioinspired materials and technology for advanced cryopreservation

M Dou, C Lu, W Rao - Trends in Biotechnology, 2022 - cell.com
Cryopreservation can help to meet the demand for biosamples of high medical value.
However, it remains difficult to effectively cryopreserve some sensitive cells, tissues, and …

Pancreatic islet cryopreservation by vitrification achieves high viability, function, recovery and clinical scalability for transplantation

L Zhan, JS Rao, N Sethia, MQ Slama, Z Han… - Nature Medicine, 2022 - nature.com
Pancreatic islet transplantation can cure diabetes but requires accessible, high-quality islets
in sufficient quantities. Cryopreservation could solve islet supply chain challenges by …

Rapid joule heating improves vitrification based cryopreservation

L Zhan, Z Han, Q Shao, ML Etheridge, T Hays… - Nature …, 2022 - nature.com
Cryopreservation by vitrification has far-reaching implications. However, rewarming
techniques that are rapid and scalable (both in throughput and biosystem size) for low …

Cryopreservation method for Drosophila melanogaster embryos

L Zhan, M Li, T Hays, J Bischof - Nature communications, 2021 - nature.com
The development of a widely adopted cryopreservation method remains a major challenge
in Drosophila research. Here we report a robust and easily implemented cryopreservation …

Inhibition Effect of Ti3C2Tx MXene on Ice Crystals Combined with Laser-Mediated Heating Facilitates High-Performance Cryopreservation

Y Cao, T Chang, C Fang, Y Zhang, H Liu, G Zhao - ACS nano, 2022 - ACS Publications
The phenomena of ice formation and growth are of great importance for climate science,
regenerative medicine, cryobiology, and food science. Hence, how to control ice formation …

Enhanced cryopreservation performance of PVA grafted monolayer graphite oxide with synergistic antifreezing effect and rapid rewarming

J Yu, J Zhang, W Han, B Liu, W Guo, L Li, N Li… - … Science and Technology, 2024 - Elsevier
In cryopreservation of biological samples such as cells, the formation, growth and
recrystallization of ice crystals can cause fatal mechanical damage to cells. Therefore, how …

Synergistic ice inhibition effect enhances rapid freezing cryopreservation with low concentration of cryoprotectants

T Chang, OA Moses, C Tian, H Wang, L Song… - Advanced …, 2021 - Wiley Online Library
Despite recent advances in controlling ice formation and growth, it remains a challenge to
design anti‐icing materials in various fields from atmospheric to biological cryopreservation …

Engineered compounds to control ice nucleation and recrystallization

N William, S Mangan, RN Ben… - Annual Review of …, 2023 - annualreviews.org
One of the greatest concerns in the subzero storage of cells, tissues, and organs is the ability
to control the nucleation or recrystallization of ice. In nature, evidence of these processes …

Cryopreservation in the era of cell therapy: revisiting fundamental concepts to enable future technologies

B Bai, C Xue, Y Wen, J Lim, Z Le… - Advanced Functional …, 2023 - Wiley Online Library
Cryopreservation strives to maximize the viability and biofunctionality of cells and tissues by
cooling them to a subzero temperature to facilitate storage and delivery. This technology has …