Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Age-related macular degeneration and polypoidal choroidal vasculopathy in Asians

CW Wong, Y Yanagi, WK Lee, Y Ogura, I Yeo… - Progress in retinal and …, 2016 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
elderly people globally. It is estimated that there will be more Asians with AMD than the rest …

Significance of vascular endothelial growth factor in growth and peritoneal dissemination of ovarian cancer

S Masoumi Moghaddam, A Amini, DL Morris… - Cancer and Metastasis …, 2012 - Springer
Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis which drives
endothelial cell survival, proliferation, and migration while increasing vascular permeability …

Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox

PZ Costa, R Soares - Life sciences, 2013 - Elsevier
Diabetes mellitus (DM) is a chronic metabolic disease characterized by the presence of
hyperglycemia, which can lead to many complications over time. These complications, such …

Angiogenesis in diabetes and obesity

R Cheng, J Ma - Reviews in Endocrine and Metabolic Disorders, 2015 - Springer
The prevalence of diabetes mellitus and obesity continues to increase globally. Diabetic
vascular complications are the main chronic diabetic complications and associated with …

VEGF levels in plasma in relation to metabolic control, inflammation, and microvascular complications in type-2 diabetes: a cohort study

Q Zhang, W Fang, L Ma, ZD Wang, YM Yang, YQ Lu - Medicine, 2018 - journals.lww.com
VEGF levels in plasma in relation to metabolic control, infl... : Medicine VEGF levels in plasma in
relation to metabolic control, inflammation, and microvascular complications in type-2 diabetes …

Polypoidal choroidal vasculopathy in Asians

CW Wong, TY Wong, CMG Cheung - Journal of clinical medicine, 2015 - mdpi.com
Age related macular degeneration (AMD) in Asians has been suggested to differ from their
Western counterparts in terms of epidemiology, pathogenesis, clinical presentation and …

Common genetic variants and pathways in diabetes and associated complications and vulnerability of populations with different ethnic origins

SS Shoily, T Ahsan, K Fatema, AA Sajib - Scientific Reports, 2021 - nature.com
Diabetes mellitus is a complex and heterogeneous metabolic disorder which is often pre-or
post-existent with complications such as cardiovascular disease, hypertension …

Hyperglycemic conditions induce rapid cell dysfunction-promoting transcriptional alterations in human aortic endothelial cells

O Bayaraa, CK Inman, SA Thomas, F Al Jallaf… - Scientific reports, 2022 - nature.com
Hyperglycemia is a major risk factor in the development of diabetic complications and
promotes vascular complications through dysregulation of endothelial cell function. Various …

Crosstalk between metabolic disorders and immune cells

S Saitoh, K Van Wijk, O Nakajima - International Journal of Molecular …, 2021 - mdpi.com
Metabolic syndrome results from multiple risk factors that arise from insulin resistance
induced by abnormal fat deposition. Chronic inflammation owing to obesity primarily results …