Immune modulation by mesenchymal stem cells

W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Concise review: mesenchymal stem cells: from roots to boost

A Andrzejewska, B Lukomska, M Janowski - Stem cells, 2019 - academic.oup.com
It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …

Biological functions of mesenchymal stem cells and clinical implications

A Naji, M Eitoku, B Favier, F Deschaseaux… - Cellular and Molecular …, 2019 - Springer
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

X Wu, J Jiang, Z Gu, J Zhang, Y Chen, X Liu - Stem cell research & …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity

Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

[HTML][HTML] Secretion of immunoregulatory cytokines by mesenchymal stem cells

D Kyurkchiev, I Bochev… - World journal of stem …, 2014 - ncbi.nlm.nih.gov
According to the minimal criteria of the International Society of Cellular Therapy,
mesenchymal stem cells (MSCs) are a population of undifferentiated cells defined by their …

Interactions between mesenchymal stem cells and the immune system

N Li, J Hua - Cellular and Molecular Life Sciences, 2017 - Springer
In addition to being multi-potent, mesenchymal stem cells (MSCs) possess
immunomodulatory functions that have been investigated as potential treatments in various …

Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications

ME Castro-Manrreza… - Journal of immunology …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …

Immunomodulatory effects of mesenchymal stromal cells-derived exosome

W Chen, Y Huang, J Han, L Yu, Y Li, Z Lu, H Li… - Immunologic …, 2016 - Springer
The mechanisms underlying immunomodulatory ability of mesenchymal stromal cells
(MSCs) remain unknown. Recently, studies suggested that the immunomodulatory activity of …