Importance COVID-19 is associated with clinically significant symptoms despite resolution of
the acute infection (ie, post-COVID-19 syndrome). Fatigue and cognitive impairment are …

Introduction COVID-19 has a wide range of clinical manifestations. Neurological
manifestations in COVID-19 patients were demonstrated during the pandemic, including …

Background Cognitive manifestations associated with the severity of a novel coronavirus
(COVID-19) infection are unknown. An early detection of neuropsychological manifestations …

Late-life depression occurring in older adults is common, recurrent, and malignant. It is
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …

Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region
differentiate and proliferate into new neurons and other resident brain cells, is known to be …

Long-term persistent symptoms of COVID-19 affect 30–80% of patients who have recovered
from the disease and may continue for a long time after the disease has been overcome …

Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …

The prevalence of obesity is growing and now includes at least one-third of the adult
population in the United States. As obesity and dementia rates reach epidemic proportions …

Systemic immune activation has emerged as an essential component of the
immunopathogenesis of HIV. It not only leads to faster disease progression, but also to …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …