In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …

Growing evidence for intratumour heterogeneity informs us that single-site biopsies fall short
of revealing the complete genomic landscape of a tumour. With an expanding repertoire of …

Photodynamic therapy (PDT) is ineffective against deeply seated metastatic tumors due to
poor penetration of the excitation light. Herein, we developed a biomimetic nanoreactor (bio …

A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes
and paclitaxel-loaded polymeric nanoparticles (PPNs)(cell-membrane-coated PPNs) …

The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …

Cancer is a leading cause of mortality worldwide. Cell membrane-coated nanocarriers
actively targeting tumor sites are known to circumvent the limitations of conventional …

Malignant transformation of cells is associated with aberrant glycosylation presented on the
cell-surface. Commonly observed changes in glycan structures during malignancy …

The major cause of cancer-associated mortality is tumor metastasis, a disease that is far
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …

Pancreatic cancer remains a lethal malignancy with poor prognosis owing to therapeutic
resistance, frequent recurrence and the absence of treatment strategies that specifically …