The anti-cancer effect of quercetin: molecular implications in cancer metabolism

M Reyes-Farias, C Carrasco-Pozo - International journal of molecular …, 2019 - mdpi.com
Cancer is a problem with worldwide importance and is the second leading cause of death
globally. Cancer cells reprogram their metabolism to support their uncontrolled expansion …

Quercetin derivatives: Drug design, development, and biological activities, a review

SR Alizadeh, MA Ebrahimzadeh - European journal of medicinal chemistry, 2022 - Elsevier
More studies are needed to develop new drugs for problems associated with drug
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …

Natural phenolic antioxidants electrochemistry: Towards a new food science methodology

AM Chiorcea‐Paquim, TA Enache… - … Reviews in Food …, 2020 - Wiley Online Library
Natural phenolic compounds are abundant in the vegetable kingdom, occurring mainly as
secondary metabolites in a wide variety of chemical structures. Around 10,000 different plant …

Nanomaterials loaded with Quercetin as an advanced tool for cancer treatment

C Caro, M Pourmadadi, MM Eshaghi… - Journal of Drug Delivery …, 2022 - Elsevier
Cancer is a major global problem ranking as the second/third cause of death, irrespective of
the region or the socio-economic situation. Quercetin (QCT), a flavonoid compound almost …

Quercetin inhibits the production of IL-1β-induced inflammatory cytokines and chemokines in ARPE-19 cells via the MAPK and NF-κB signaling pathways

SC Cheng, WC Huang, JH S. Pang, YH Wu… - International journal of …, 2019 - mdpi.com
Quercetin, a bioflavonoid derived from vegetables and fruits, exerts anti-inflammatory effects
in various diseases. Our previous study revealed that quercetin could suppress the …

The impact of matrix metalloproteinase-9 on the sequential steps of the metastatic process

G Barillari - International journal of molecular sciences, 2020 - mdpi.com
In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

Ethosomes and transethosomes as cutaneous delivery systems for quercetin: A preliminary study on melanoma cells

F Ferrara, M Benedusi, M Sguizzato, R Cortesi… - Pharmaceutics, 2022 - mdpi.com
The present study is aimed to design ethosomes and transethosomes for topical
administration of quercetin. To overcome quercetin low bioavailability, scarce solubility and …

Quercetin enhanced paclitaxel therapeutic effects towards PC-3 prostate cancer through ER stress induction and ROS production

X Zhang, J Huang, C Yu, L Xiang, L Li… - OncoTargets and …, 2020 - Taylor & Francis
Introduction Prostate cancer is one of the most common cancers threatening public health
worldwide. Although chemotherapy plays an important role in treating prostate cancer, it …

Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy

K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
Natural prodrugs derived from different natural origins (eg, medicinal plants, microbes,
animals) have a long history in traditional medicine. They exhibit a broad range of …

Quercetin induces apoptosis in glioblastoma cells by suppressing Axl/IL-6/STAT3 signaling pathway

HI Kim, SJ Lee, YJ Choi, MJ Kim, TY Kim… - The American Journal of …, 2021 - World Scientific
Gliomas are the mostly observed form of primary brain tumor, and glioblastoma multiforme
(GBM) shows the highest incidence. The survival rate of GBM is fairly poor; thus, discovery of …