Glaucoma in adults—screening, diagnosis, and management: a review

JD Stein, AP Khawaja, JS Weizer - Jama, 2021 - jamanetwork.com
Importance Glaucoma is the most common cause of irreversible blindness worldwide. Many
patients with glaucoma are asymptomatic early in the disease course. Primary care …

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

H Li, Y Yang, W Hong, M Huang, M Wu… - Signal transduction and …, 2020 - nature.com
Based on engineered or bacterial nucleases, the development of genome editing
technologies has opened up the possibility of directly targeting and modifying genomic …

Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices

MD Abràmoff, PT Lavin, M Birch, N Shah… - NPJ digital medicine, 2018 - nature.com
Artificial Intelligence (AI) has long promised to increase healthcare affordability, quality and
accessibility but FDA, until recently, had never authorized an autonomous AI diagnostic …

[HTML][HTML] Updates on the Diagnosis and Management of Glaucoma

IV Wagner, MW Stewart, SK Dorairaj - Mayo Clinic Proceedings …, 2022 - Elsevier
Glaucoma is the leading cause of blindness throughout the world (after cataracts); therefore,
general physicians should be familiar with the diagnosis and management of affected …

The pathophysiology and treatment of glaucoma: a review

RN Weinreb, T Aung, FA Medeiros - Jama, 2014 - jamanetwork.com
Importance Glaucoma is a worldwide leading cause of irreversible vision loss. Because it
may be asymptomatic until a relatively late stage, diagnosis is frequently delayed. A general …

Artificial intelligence in ophthalmology: The path to the real-world clinic

Z Li, L Wang, X Wu, J Jiang, W Qiang, H Xie… - Cell Reports …, 2023 - cell.com
Artificial intelligence (AI) has great potential to transform healthcare by enhancing the
workflow and productivity of clinicians, enabling existing staff to serve more patients …

[HTML][HTML] Deep learning and glaucoma specialists: the relative importance of optic disc features to predict glaucoma referral in fundus photographs

S Phene, RC Dunn, N Hammel, Y Liu, J Krause… - Ophthalmology, 2019 - Elsevier
Purpose To develop and validate a deep learning (DL) algorithm that predicts referable
glaucomatous optic neuropathy (GON) and optic nerve head (ONH) features from color …

CRISPR-Cas9–based treatment of myocilin-associated glaucoma

A Jain, G Zode, RB Kasetti, FA Ran… - Proceedings of the …, 2017 - National Acad Sciences
Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss
worldwide, with elevated intraocular pressure (IOP) a major risk factor. Myocilin (MYOC) …

Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity

T Souma, SW Tompson, BR Thomson… - The Journal of …, 2016 - Am Soc Clin Investig
Primary congenital glaucoma (PCG) is a devastating eye disease and an important cause of
childhood blindness worldwide. In PCG, defects in the anterior chamber aqueous humor …

Medical management of glaucoma in the 21st century from a Canadian perspective

P Harasymowycz, C Birt, P Gooi… - Journal of …, 2016 - Wiley Online Library
Glaucoma is a medical term describing a group of progressive optic neuropathies
characterized by degeneration of retinal ganglion cells and retinal nerve fibre layer and …