L-arginine-nitric oxide-asymmetric dimethylarginine pathway and the coronary circulation: translation of basic science results to clinical practice

A Cziráki, Z Lenkey, E Sulyok, I Szokodi… - Frontiers in …, 2020 - frontiersin.org
By 1980, it was thought that we already knew most of the major mechanisms regulating
vascular tone. However, after the somewhat serendipity discovery that endothelium is …

Pericardial fluid: an underrated molecular library of heart conditions and a potential vehicle for cardiac therapy

F Trindade, R Vitorino, A Leite-Moreira… - Basic research in …, 2019 - Springer
The remote but heart-encircling location of pericardial fluid confers this biofluid unique
properties. Once past the limitation of the invasive collection, for instance, on occasion of …

Nitric oxide-related biological pathways in patients with major depression

A Baranyi, O Amouzadeh-Ghadikolai… - PloS one, 2015 - journals.plos.org
Background Major depression is a well-known risk factor for cardiovascular diseases and
increased mortality following myocardial infarction. However, biomarkers of depression and …

An overview of human pericardial space and pericardial fluid

AF Hassanabad, A Zarzycki, JF Deniset… - Cardiovascular …, 2021 - Elsevier
The pericardium is a double-layered fibro-serous sac that envelops the majority of the
surface of the heart as well as the great vessels. Pericardial fluid is also contained within the …

The predictive role of plasma biomarkers in the evolution of aortopathies associated with congenital heart malformations

A Făgărășan, MO Săsăran - International Journal of Molecular Sciences, 2022 - mdpi.com
Dilatation of the aorta is a constantly evolving condition that can lead to the ultimate life-
threatening event, acute aortic dissection. Recent research has tried to identify quantifiable …

Biomarcadores de função endotelial em doenças cardiovasculares: hipertensão

JA Neves, JA Neves, RCM Oliveira - Jornal Vascular Brasileiro, 2016 - SciELO Brasil
A incidência de hipertensão arterial sistêmica está aumentando mundialmente. Sua
prevenção baseia-se na identificação dos hipertensos. Atualmente, biomarcadores são …

Association of asymmetric dimethylarginine and diastolic dysfunction in patients with hypertrophic cardiomyopathy

K Cordts, D Seelig, N Lund, L Carrier, RH Böger… - Biomolecules, 2019 - mdpi.com
Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common
in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may contribute to myocardial …

[HTML][HTML] Biomarkers of endothelial function in cardiovascular diseases: hypertension

JA Neves, JA Neves, RCM Oliveira - Jornal Vascular Brasileiro, 2016 - SciELO Brasil
A incidência de hipertensão arterial sistêmica está aumentando mundialmente. Sua
prevenção baseia-se na identificação dos hipertensos. Atualmente, biomarcadores são …

Cardiovascular adaptations and inflammation in marathon runners

K Tsarouhas, C Tsitsimpikou… - Experimental and …, 2022 - spandidos-publications.com
Long‑distance running has become increasingly popular. Cardiovascular adaptations to
exercise are relevant to the specific sports and this is also the case in long‑distance running …

Novel molecular insights and potential approaches for targeting hypertrophic cardiomyopathy: focus on coronary modulators

T Pasqua, T Tropea, MC Granieri, A De Bartolo… - Vascular …, 2022 - Elsevier
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder that associates with
nucleotide sequence variants in genes encoding sarcomere related proteins, and is …