Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

The majority of critically ill intensive care unit (ICU) patients with severe sepsis develop ICU-
acquired weakness (ICUAW) characterized by loss of muscle mass, reduction in myofiber …

Myosteatosis is the pathologic accumulation of lipid that can occur in conjunction with
atrophy and fibrosis following skeletal muscle injury. Little is known about the mechanisms …

Cachexia is an exacerbating event in many types of cancer that is strongly associated with a
poor prognosis. We have identified cytokine, signaling, and transcription factors that are …

Background Critically ill patients frequently develop muscle atrophy and weakness in the
intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. Sepsis …

Decline in skeletal muscle cell size (myofiber atrophy) is a key feature of cancer-induced
wasting (cachexia). In particular, atrophy of the diaphragm, the major muscle responsible for …

Background Skeletal muscle atrophy involves and requires widespread changes in skeletal
muscle gene expression and signaling pathway, resulting in excessive loss of muscle mass …

Skeletal muscle wasting occurs in both chronic and acute diseases. Increasing evidence
has shown this debilitating process is associated with short-and long-term outcomes in …

New findings• What is the topic for this review? An up‐to‐date analysis on the role of nuclear
factor‐κB signaling and transcriptional control in adult skeletal muscle atrophy.• What …

Sex steroids influence the maintenance and growth of muscles. Decline in androgens,
estrogens and progesterone by aging leads to the loss of muscular function and mass …