Meiosis: dances between homologs

D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Meiotic recombination: the essence of heredity

N Hunter - Cold Spring Harbor perspectives in biology, 2015 - cshperspectives.cshlp.org
The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

[HTML][HTML] Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage

S Durand, Q Lian, J Jing, M Ernst, M Grelon… - Nature …, 2022 - nature.com
Meiotic crossovers are limited in number and are prevented from occurring close to each
other by crossover interference. In many species, crossover number is subject to sexual …

The synaptonemal complex imposes crossover interference and heterochiasmy in Arabidopsis

L Capilla-Pérez, S Durand, A Hurel… - Proceedings of the …, 2021 - National Acad Sciences
Meiotic crossovers (COs) have intriguing patterning properties, including CO interference,
the tendency of COs to be well-spaced along chromosomes, and heterochiasmy, the marked …

Recombination, pairing, and synapsis of homologs during meiosis

D Zickler, N Kleckner - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Recombination is a prominent feature of meiosis in which it plays an important role in
increasing genetic diversity during inheritance. Additionally, in most organisms …

Addressing research bottlenecks to crop productivity

M Reynolds, OK Atkin, M Bennett, M Cooper… - Trends in Plant …, 2021 - cell.com
Asymmetry of investment in crop research leads to knowledge gaps and lost opportunities to
accelerate genetic gain through identifying new sources and combinations of traits and …

ZYP1 is required for obligate cross-over formation and cross-over interference in Arabidopsis

MG France, J Enderle, S Röhrig… - Proceedings of the …, 2021 - National Acad Sciences
The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between
homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is …

The molecular biology of meiosis in plants

R Mercier, C Mézard, E Jenczewski… - Annual review of …, 2015 - annualreviews.org
Meiosis is the cell division that reshuffles genetic information between generations.
Recently, much progress has been made in understanding this process; in particular, the …

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

B Silva, R Pentz, AM Figueira, R Arora, YW Lee… - Nature …, 2019 - nature.com
Telomerase negative immortal cancer cells elongate telomeres through the Alternative
Lengthening of Telomeres (ALT) pathway. While sustained telomeric replicative stress is …

Meiotic recombination: mixing it up in plants

Y Wang, GP Copenhaver - Annual Review of Plant Biology, 2018 - annualreviews.org
Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …