This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Nanoparticle size plays a central role in determining material properties and performance in
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …

Alzheimer's disease (AD) is one of the biggest human health threats due to increases in
aging of the global population. Unfortunately, drugs for treating AD have been largely …

Radio-resistance of glioblastoma (GBM) remains a leading cause of radiotherapy failure
because of the protective autophagy induced by X-Ray irradiation and tumor cells' strong …

Protein misfolding and aggregation have attracted immense research interests due to their
connection with an array of degenerative diseases including neurodegenerative disorders …

Conspectus Nanoparticles are widely used in various biomedical applications as drug
delivery carriers, imaging probes, single-molecule tracking/detection probes, artificial …

Huntington's disease (HD) is a neurological disorder characterized by a reduction in
medium-spiny neurons in the brain. Currently, there is no cure for HD and treatment relies …

Conspectus Protein aggregation is associated with different human diseases such as
Alzheimer's, Huntington's, Parkinson's, diabetes type II, and cataracts. Currently no effective …

The concept of developing novel anti-amyloid inhibitors in the scientific community has
engrossed remarkable research interests and embraced significant potential to resolve …