Single-cell analysis targeting the proteome

M Labib, SO Kelley - Nature Reviews Chemistry, 2020 - nature.com
The existence of cellular heterogeneity and its central relevance to biological phenomena
provides a strong rationale for a need for analytical methods that enable analysis at the …

Biosensor technology: recent advances in threat agent detection and medicine

J Kirsch, C Siltanen, Q Zhou, A Revzin… - Chemical Society …, 2013 - pubs.rsc.org
Biosensors are of great significance because of their capability to resolve a potentially large
number of analytical problems and challenges in very diverse areas such as defense …

Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery

Z Liu, S Tabakman, K Welsher, H Dai - Nano research, 2009 - Springer
Carbon nanotubes exhibit many unique intrinsic physical and chemical properties and have
been intensively explored for biological and biomedical applications in the past few years. In …

[HTML][HTML] Protein immobilization techniques for microfluidic assays

D Kim, AE Herr - Biomicrofluidics, 2013 - pubs.aip.org
Microfluidic systems have shown unequivocal performance improvements over conventional
bench-top assays across a range of performance metrics. For example, specific advances …

Toxicity and environmental risks of nanomaterials: challenges and future needs

PC Ray, H Yu, PP Fu - … of Environmental Science and Health Part …, 2009 - Taylor & Francis
Nanotechnology has gained a great deal of public interest because of the needs and
applications of nanomaterials in many areas of human endeavors including industry …

Biological applications of functionalized calixarenes

SB Nimse, T Kim - Chemical Society Reviews, 2013 - pubs.rsc.org
The functionalized calixarene derivatives exhibit remarkable properties towards organic and
bioorganic molecules. However, the ability of calixarene derivatives to form stable …

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

C Ma, R Fan, H Ahmad, Q Shi, B Comin-Anduix… - Nature medicine, 2011 - nature.com
Cellular immunity has an inherent high level of functional heterogeneity. Capturing the full
spectrum of these functions requires analysis of large numbers of effector molecules from …

[HTML][HTML] Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells

S Wang, H Wang, J Jiao, KJ Chen… - … (International ed. in …, 2009 - ncbi.nlm.nih.gov
During the progression of metastasis, cancer cells detach from the solid primary tumor, enter
the blood stream, and travel to different tissues of the body. These breakaway cancer cells in …

Programmed synthesis of three-dimensional tissues

ME Todhunter, NY Jee, AJ Hughes, MC Coyle… - Nature …, 2015 - nature.com
Reconstituting tissues from their cellular building blocks facilitates the modeling of
morphogenesis, homeostasis and disease in vitro. Here we describe DNA-programmed …

Chemical strategies for generating protein biochips

P Jonkheijm, D Weinrich, H Schröder… - Angewandte Chemie …, 2008 - Wiley Online Library
Protein biochips are at the heart of many medical and bioanalytical applications. Increasing
interest has been focused on surface activation and subsequent functionalization strategies …