Tissue repair and wound healing are complex processes that involve inflammation, granulation, and remodeling of the tissue. The potential of various statins including …
Despite the status of atorvastatin (AT) as one of the top selling statins for prophylaxis against primary and secondary cardiovascular diseases, its limited oral absorption limits its full …
W Dong, X Su, M Xu, M Hu, Y Sun, P Zhang - Asian journal of …, 2018 - Elsevier
Due to low solubility and bioavailability, atorvastatin calcium is confronted with challenge in conceiving appropriate formulation. Solid dispersion of atorvastatin calcium was prepared …
MA Shaker, HM Elbadawy, SS Al Thagfan… - International Journal of …, 2021 - Elsevier
Despite the fact that atrovastatin (At) is being one of the bestselling statins used to prevent complicated cardiovascular diseases, its low oral bioavailability decreases its clinical …
A Rossetti, DA Real, BA Barrientos… - International Journal of …, 2024 - Elsevier
Atorvastatin (ATV) is a first-line drug for the treatment of hyperlipidemia. This drug presents biopharmaceutical problems, partly due to its low solubility and dissolution rate. In this work …
MA Shaker - Journal of Drug Delivery Science and Technology, 2018 - Elsevier
Atorvastatin (Atv) is one of antihyperlipidimic drugs characterized by limited oral bioavailability due to its low solubility-despite its high permeability-that hinders its full clinical …
R Kong, X Zhu, ES Meteleva, NE Polyakov… - Drug Delivery and …, 2018 - Springer
The aim of the present investigation was to enhance the solubility and dissolution of atorvastatin calcium (ATV), a poorly water-soluble drug with larch polysaccharide …
Atorvastatin (ATV) is a poorly water-soluble drug that exhibits poor oral bioavailability. Therefore, present research was designed to develop ATV solid dispersions (SDs) to …
Atorvastatin (ATR) is a poorly soluble anti-hyperlipidemic drug. The drug belongs to the class II group according to the biopharmaceutical classification system (BCS) with low …