Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …

Patients with cancer have a higher risk of severe coronavirus disease (COVID-19) and
associated mortality than the general population. Owing to this increased risk, patients with …

INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …

The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if
coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this …

Monoclonal antibodies (mAbs) are often selected from antigen-specific single B cells
derived from different hosts, which are notably short-lived in ex vivo culture conditions and …

2018 marks the 100-year anniversary of the 1918 influenza pandemic, which killed~ 50
million people worldwide. The severity of this pandemic resulted from a complex interplay …

The present vaccine against influenza virus has the inevitable risk of antigenic discordance
between the vaccine and the circulating strains, which diminishes vaccine efficacy. This …

Antibody responses to viral infections are sustained for decades by long-lived plasma cells
(LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19 …