Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery

F Davodabadi, SF Sajjadi, M Sarhadi… - European Journal of …, 2023 - Elsevier
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …

Pharmacological properties of trichostatin A, focusing on the anticancer potential: A comprehensive review

A Bouyahya, N El Omari, M Bakha, T Aanniz… - Pharmaceuticals, 2022 - mdpi.com
Trichostatin A (TSA), a natural derivative of dienohydroxamic acid derived from a fungal
metabolite, exhibits various biological activities. It exerts antidiabetic activity and reverses …

Dual pH-and temperature-responsive poly (dimethylaminoethyl methacrylate)-coated mesoporous silica nanoparticles as a smart drug delivery system

S Ramezanian, J Moghaddas… - Scientific Reports, 2023 - nature.com
A robust drug delivery system was created by grafting poly (dimethylaminoethyl
methacrylate)(PDMAEMA) onto silica nanoparticles with two different lengths using an in situ …

Carvacrol-fabricated chitosan nanoparticle synergistic potential with topoisomerase inhibitors on breast and cervical cancer cells

A Akhlaq, M Ashraf, MO Omer, I Altaf - ACS omega, 2023 - ACS Publications
Breast and cervical cancers are the most common heterogeneous malignancies in women.
Chemotherapy with conventional drug delivery systems having several limitations along with …

Targeting MCL1 with Sanggenon C overcomes MCL1-driven adaptive chemoresistance via dysregulation of autophagy and endoplasmic reticulum stress in cervical …

W Sun, H Cai, K Zhang, H Cui, E Zhao - Phytomedicine, 2024 - Elsevier
Background Cervical cancer ranks as one of the most prevalent malignancies among
women worldwide and poses a significant threat to health and quality of life. MCL1 is an …

Cellulose nanocrystals based delivery vehicles for anticancer agent curcumin

R Kumar, S Chauhan - International Journal of Biological Macromolecules, 2022 - Elsevier
Cancer is a complex disease that starts with genetic alterations and mutations in healthy
cells. The past decade has witnessed a huge demand for new biocompatibility and high …

The regulatory functions and the mechanisms of long non-coding RNAs in cervical cancer

Q Yang, A Al-Hendy - Cells, 2022 - mdpi.com
Cervical cancer is one of the leading causes of death in gynecology cancer worldwide. High-
risk human papillomaviruses (HPVs) are the major etiological agents for cervical cancer …

Unveiling the multitargeted repurposing potential of taxifolin (dihydroquercetin) in cervical cancer: An extensive MM\GBSA-based screening, and MD simulation study

HH Almasoudi, MA Hakami, AY Alhazmi, M Makkawi… - Medical Oncology, 2023 - Springer
Cervical cancer is a significant cause of morbidity and mortality in women worldwide.
Despite the availability of effective therapies, the development of drug resistance and …

Unveiling the multitargeted potency of Sodium Danshensu against cervical cancer: a multitargeted docking-based, structural fingerprinting and molecular dynamics …

S Alghamdi, HM Baeissa, M Azhar Kamal… - Journal of …, 2024 - Taylor & Francis
Cervical Cancer (CC) is one of the most common types of cancer in women worldwide, with
a significant number of deaths reported yearly. Despite the various treatment options …

Progresses in nano-enabled platforms for the treatment of vaginal disorders

R Patel, BK Yadav, G Patel - Recent Patents on Nanotechnology, 2023 - benthamdirect.com
Background: The most common vaginal disorders are within the uterus. According to the
latest statistics, vaginal disorders occur in 50% to 60% of females. Although curative …